第一部分：指南、共识与标准制定我科主导制定的指南

1. 中国万古霉素治疗药物监测指南（中国药理学会）

2. 伏立康唑个体化用药指南（中国药理学会）

3. 人血白蛋白用于肝硬化治疗的快速建议指南（中国药学会医院药学专业委员会，中华医学会肝病学分会）

4. 儿科阿奇霉素注射使用的快速建 议指南（中国药理学会，中华医学会儿科学分会呼吸学组）

5. 基于肠促胰素治疗药物临床应用的快速建议指南（中华医学会内分泌学分会，中国药学会医院药学专业委员会）

6. 严重过敏反应急救指南（国家卫生健康委员会医疗管理服务指导中心、中国药理学会药源性疾病学专业委员会、中国医师协会变态反应医师分会、中华医学会变态反应学分会、中华医学会急诊医学分会、中华医学会呼吸病学分会、中华医学会麻醉医学分会、中国药学会医院药学专业委员会和中华护理学会）

7. 我国高警示药品推荐目录2019版，（中国药学会医院药学专业委员会用药安全专家组）http://www.psmchina.cn/psm/specialtopic/jsyp/jsyp.html

8. 新型冠状病毒感染：医院药学工作指导与防控策略专家共识（中国药学会）

9. 冠状病毒(SARS-CoV-2)暴发:适用于药师和药房工作人员的信息与试行指南.（国际药学联合会，翻译）

10.Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidencebased guideline

我科参与制定的指南

1. 参与《医疗机构短缺药品管理指南》 （国家卫健委），子课题负责人

2. 参与《医疗机构短缺药品分类分级与替代遴选使用技术指南》（国家卫健委），子课题负责人

3. 参与《中国血栓性疾病防治指南》，专科负责人

标准制定

1. 主导制定北京市地方标准《静脉用药集中调配规范》，（北京市市场监督管理局），2019.12.25

2. 参与团体标准：中国医院质量安全管理（第3-2部分：医疗保障 药品保障）T/CHAS 10-3-2—2019

3. 参与团体标准：中国医院质量安全管理（第2-12部分：患者服务 临床用药）T/CHAS 10—2—12—2019

第二部分：近3年著作成果

1. 新型冠状病毒肺炎常用中成药实用手册（中文版）.杨毅恒.主编.化学工业出版社.2020

2. 临床常用方剂与中成药.杨毅恒.副主编.人民卫生出版社.2020

3. 社区医疗机构常用药品处方集.翟所迪.主编.中国协和医科大学出版社.2020

4. 用药安全.刘芳.主译.科学技术文献出版社.2019

5. 药物治疗学.翟所迪.主编.国家开放大学出版社.2019

6. 国际药学联合会（FIP）医院药学未来发展的巴塞尔共识（2015版）释义——中国思考与实践.翟所迪.主编.北京大学医学出版社.2018

7. 用药错误.刘芳.主编.人民卫生出版社.2018

8. 高风险用药人群循证用药手册（儿童分册）.赵荣生.副主编.人民卫生出版社.2018

9. 全国临床药师规范化培训系列教材：呼吸内科专业.翟所迪.主编.人民卫生出版社.2018

10.用药错误.张晓乐.主编.人民卫生出版社.2017

11.老年用药基本知识.张晓乐.主编.中央广播电视大学出版社.2017

第三部分：近3年发表文章

1. 2020.Efficacy and safety of antiviral agents in COVID-19 patients: systematic review and meta-analysis.Article.CMAJ.6.938

2. 2020.Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline.Article.CMAJ.6.938

3. 2020.Anti-RAS drugs and SARS-CoV-2 infection.letter.Acta Pharm Sin B.5.808

4. 2020.Fighting against COVID-19: Innovative strategies for clinical pharmacists.Article.Res Social Adm Pharm.2.719

5. 2020.Hospital pharmacists' pharmaceutical care for hospitalized patients with COVID-19: Recommendations and guidance from clinical experience.Article.Res Social Adm Pharm.2.719

6. 2020.Recommendations and guidance for providing pharmaceutical care services during COVID-19 pandemic: A China perspective.Article.Res Social Adm Pharm.2.719

7. 2020.The Incidence and Risk Factors for Adverse Drug Reactions Related to Tanreqing Injection: A Large Population-Based Study in China.Article.Frontiers in Pharmacology.3.845

8. 2019.Guideline for [Clinical Guidelines Constitution/Amendment] in China.Article.INTERNATIONAL JOURNAL FOR QUALITY IN HEALTH CARE.1.829

9. 2019.Prostate cancer with bone metastasis in Beijing: an observational study of prevalence, hospital visits and treatment costs using data from an administrative claims database.论著.BMJ Open.2.376

10.2019.Comparison of lixisenatide in combination with basal insulin vs other insulin regimens for the treatment of patients with type 2 diabetes inadequately controlled by basal insulin: Systematic review, network meta-analysis and cost-effectiveness analysis.Article.DIABETES OBESITY & METABOLISM.6.133

11.2019.Optimising early nutritional support for medical inpatients.letter.LANCET.59.102

12.2019.The efficacy and safety of menatetrenone in the management of osteoporosis: a systematic review and meta-analysis of randomized controlled trials.Review.OSTEOPOROSIS INTERNATIONAL.3.83

13.2019.The Benefit of Individualized Vancomycin Dosing Via Pharmacokinetic Tools: A Systematic Review and Meta-analysis.Review.ANNALS OF PHARMACOTHERAPY.2.443

14.2019.Ulinastatin treatment for acute respiratory distress syndrome in China: a meta-analysis of randomized controlled trials.Article.BMC Pulmonary Medicine.2.184

15.2019.Pantoprazole in Patients in the ICU.letter.NEW ENGLAND JOURNAL OF MEDICINE.70.67

16.2019.Model-based Voriconazole Dose Optimization in Chinese Adult Patients With Hematologic Malignancies.Article.CLINICAL THERAPEUTICS.2.935

17.2019.Severe toxic effects of low‐dose methotrexate treatment for placenta accreta in a patient with methylenetetrahydrofolate reductase mutations.Article.JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS.2.167

18.2019.Is De-escalated Bisphosphonates Therapy a Suitable Alternative to Standard Dosing in Malignant Tumor Patients With Bone Metastases: A Systematic Review and Meta-Analysis.Review.Frontiers in Oncology.4.137

19.2019.Lixisenatide versus insulin glulisine on top of insulin glargine in patients with type 2 diabetes mellitus: a cost-per-responder analysis in China..Article.CURRENT MEDICAL RESEARCH AND OPINION.2.345

20.2019.Efficacy and safety of sertraline for the treatment of premature ejaculation: systematic review and meta-analysis.Article.medicine.1.87

21.2019.Treatment patterns of prostate cancer with bone metastasis in Beijing: A real‐world study using data from an administrative claims database.Article.PHARMACOEPIDEMIOLOGY AND DRUG SAFETY.2.87

22.2019.Association of atorvastatin with the risk of hepatotoxicity: a pilot prescription sequence symmetry analysis.论著.Therapeutics and Clinical Risk Management.1.824

23.2019.Effect of dipeptidyl-peptidase-4 inhibitors on C-reactive protein in patients with type 2 diabetes: a systematic review and meta-analysis.Review.Lipids in Health and Disease.2.651

24.2019.Levetiracetam for epilepsy: an evidence map of efficacy, safety and economic profiles.Article.Neuropsychiatric Disease and Treatment.2.228

25.2018.Cost-effectiveness analysis of amisulpride and olanzapine for patients with schizophrenia in China.Meeting Abstract.VALUE IN HEALTH.5.037

26.2018.Prior anti-CAFs break down the CAFs barrier and improve accumulation of docetaxel micelles in tumor.Article.International Journal of Nanomedicine.4.471

27.2018.Individualized Medication of Voriconazole: A Practice Guideline of the Division of Therapeutic Drug Monitoring,Chinese Pharmacological Society.Review.THERAPEUTIC DRUG MONITORING.2.092

28.2018.Rare heparin induced thrombocytopenia type I reaction in a hemodialysis patient.Article.Medicine.2.028

29.2018.Posaconazole-associated severe hyperbilirubinemia in acute myeloid leukemia following chemotherapy: A case report.Article.WORLD JOURNAL OF CLINICAL CASES.1.931

30.2018.Risks of diabetic foot syndrome and amputation associated with sodium glucose co-transporter 2 inhibitors: A Meta-analysis of Randomized Controlled Trials.Article.DIABETES & METABOLISM.3.744

31.2018.Drug?induced anaphylaxis in China: a 10 year retrospective analysis of the Beijing Pharmacovigilance Database.Article.International Journal of Clinical Pharmacy.1.508

32.2018.Development and validation of an algorithm to identify drug?induced anaphylaxis in the Beijing Pharmacovigilance Database.Article.International Journal of Clinical Pharmacy.1.508

33.2018.Traditional Chinese medicine and drug?induced anaphylaxis: data from the Beijing pharmacovigilance database.Article.International Journal of Clinical Pharmacy.1.508

34.2018.Nebulized Corticosteroids in the Treatment of COPD Exacerbations:Systematic Review, Meta-Analysis, and Clinical Perspective.Review.Respiratory Care.2.073

35.2018.Blocking Autophagic Flux Enhances Iron Oxide Nanoparticle Photothermal Therapeutic Efficiency in Cancer Treatment.Article.ACS Appl Mater Interfaces.8.097

36.2018.Simultaneous quantification of EVT201, a novel partial positive allosteric GABAA receptor modulator, and its two metabolites in human plasma by UHPLC/MS/M.Article.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2.831

37.2018.Comparative efficacy and safety between amisulpride and olanzapine in schizophrenia treatment and a cost analysis in China: a systematic review, meta-analysis, and cost-minimization analysis.Article.BMC Psychiatry.2.419

38.2018.Acid-suppressive drugs and risk of kidney disease: A systematic review and meta-analysis.Review.JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY.3.483

39.2018.Simultaneous determination of twelve polar pteridines including dihydro- and tetrahydropteridine in human urine by hydrophilic interaction liquid chromatography with tandem mass spectrometry.Article.BIOMEDICAL CHROMATOGRAPHY.1.688

40.2018.Pioglitazone and bladder cancer risk: a systematic review and meta-analysis.Review.Cancer Medicine.3.202

41.2018.A Drug-drug Interaction Between Cyclosporine and Nystatin.Article.CLINICAL THERAPEUTICS.3.185

42.2018.Efficacy and safety of saxagliptin in patients with type 2 diabetes: A systematic review and meta-analysis.Review.PLoS One.2.766

43.2018.Comparisons of diabetic retinopathy events associated with glucose-lowering drugs in patients with type 2 diabetes mellitus: A network meta-analysis.Article.DIABETES OBESITY & METABOLISM.5.98

44.2018.Use of antihypertensive drugs and risk of keratinocyte carcinoma: A meta‐analysis of observational studies.Article.PHARMACOEPIDEMIOLOGY AND DRUG SAFETY.2.314

45.2018.Levodopa/carbidopa/entacapone versus levodopa/dopa-decarboxyiase inhibitor for the treatment of Parkinson's disease: systematic review, meta-analysis, and economic evaluation.Article.Therapeutics and Clinical Risk Management.1.995

46.2018.Use of Antihypertensive Drugs and Risk of Malignant Melanoma: A Meta-analysis of Observational Studies.Review.DRUG SAFETY.3.435

47.2018.Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report..Article.EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY.2.679

48.2018.Clinical features and treatment of pediatric patients with drug-induced anaphylaxis: a study based on pharmacovigilance data.Article.EUROPEAN JOURNAL OF PEDIATRICS.2.242

49.2017.Determination of amino acids in colon cancer cells by using UHPLC-MS/MS and [U-13C5]-glutamine as the isotope tracer.Article.TALANTA.4.916

50.2017.The influence of combination use of CYP450 inducers on the pharmacokinetics of voriconazole: a systematic review.Review.JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS.1.679

51.2017.Dipeptidyl peptidase-4 inhibitors and risk of arthralgia: A systematic review and meta-analysis.Review.DIABETES & METABOLISM.4.101

52.2017.Cost-effectiveness analysis of dapagliflozin versus glimepiride as monotherapy in a Chinese population with type 2 diabetes mellitus.Article.CURRENT MEDICAL RESEARCH AND OPINION.2.757

53.2017.Epinephrine inhibits vascular hyperpermeability during platelet activating factor or ovalbumin induced anaphylaxis.Article.RSC Advances.3.108

54.2017.Sodium-glucose co-transporter-2 inhibitors and risk of adverse renal outcomes among patients with type 2 diabetes: A network and cumulative meta-analysis of randomized controlled trials.Article.DIABETES OBESITY & METABOLISM.6.715

55.2017.SGLT2 inhibitors and risk of cancer in type 2 diabetes: a systematic review and meta-analysis of randomised controlled trials.Article.DIABETOLOGIA.6.08

56.2017.Phosphodiesterase type 5 inhibitors and risk of melanoma: A meta-analysis.Article.JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY.7.002

57.2017.Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: A meta-analysis of randomized controlled trials.Article.DIABETES OBESITY & METABOLISM.6.715

58.2017.Efficacy and Safety of Lomitapide in Hypercholesterolemia.Review.American Journal of Cardiovascular Drugs.2.768

59.2017.Use of Epinephrine in Patients with Drug-Induced Anaphylaxis: An Analysis of the Beijing Pharmacovigilance Database.Article.INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY.2.72

60.2017.Comparison of prophylactic effect of UGIB and effects on platelet function between PPIs and H2RAs combined with DAPT: systematic review and meta-analysis.Article.Therapeutics and Clinical Risk Management.2.2

61.2017.Calcineurin inhibitors versus cyclophosphamide for idiopathic membranous nephropathy: A systematic review andmeta-analysis of 21 clinical trials.Review.AUTOIMMUNITY REVIEWS.8.961

62.2017.Empiric treatment against invasive fungal diseases in febrile neutropenic patients a systematic review and network meta-analysis.Review.BMC INFECTIOUS DISEASES.2.768

63.2017.An open-label, two-period comparative study on pharmacokinetics and safety of a combined ethinyl estradiol/gestodene transdermal contraceptive patch.Article.Drug Design Development and Therapy.2.822

64.2017.Post-Marketing Safety Surveillance of the Salvia Miltiorrhiza Depside Salt for Infusion: A Real World Study..Article.PLoS One.2.806

65.2017.Sodium-glucose co-transporter 2 inhibitors in addition to insulin therapy for management of type 2 diabetes mellitus: A meta-analysis of randomized controlled trials..Article.DIABETES OBESITY & METABOLISM.6.715

第四部分：近3年获得的纵向基金

纵向基金

1. 2019 .基于处方序列对称分析的常见急性药品不良反应主动监测与预警模型研究.国家自然科学基金.国家自然科学基金（青年科学基金项目）

2. 2019 .基于代谢组学和质谱成像研究色氨酸分解代谢在急性肾损伤中的作用机制.国家自然科学基金.国家自然科学基金（青年科学基金项目） .

3. 2018 .基于免疫激活与光热双功能的四氧化三铁纳米粒用于肿瘤治疗及其作用机制研究.国家自然科学基金.国家自然科学基金（青年科学基金项目） .

4. 2018 .PLA2G7 R92H基因多态性对药源性急性严重过敏反应的作用及机制研究.国家自然科学基金.国家自然科学基金（面上项目） .

5. 2018 .消化系统炎性疾病新药临床评价技术平台建设.科技部.国家科技重大专项 .

6. 2017 .药物相互作用预测模型研究.科技部.国家科技重大专项 .

7. 2017 .药物相互作用临床验证性研究.科技部.国家科技重大专项 .

8. 2017 .创新药物0期试验.科技部.国家科技重大专项 .

9. 2017 .药物一致性评价关键技术与标准研究.科技部.国家科技重大专项 .

10.2020 .基于药学知识图谱的处方审核与临床辅助决策支持 系统.北京市科学技术委员会.AI+健康协同创新培育 .

11.2019 .治疗药物监测结合计算机辅助模拟的伏立康唑个体化用药管理.学（协、基金）会及中心.北京药学会 .

12.2018 .曲普瑞林的循证评价研究.学（协、基金）会及中心.北京市卫生经济学会 .

13.2018 .原研与仿制万古霉素体外诱导MRSA耐药性的比较.学（协、基金）会及中心.北京医卫健康公益基金会 .

14.2017 .基于《中国药品综合评价指南参考大纲》对新型口服抗凝药进行经济性评价.学（协、基金）会及中心.中国健康促进基金会 .

15.2017 .异甘草酸镁治疗肝细胞损伤性疾病的卫生技术评估.学（协、基金）会及中心.北京医卫健康公益基金会 .

16.2018 .万古霉素相关肾毒性的回顾性队列研究.北京大学第三医院.院临床重点项目青年项目类 .

17.2018 .生理药动学模型在甲氨蝶呤个体化治疗中的作用.北京大学第三医院.院回国人员启动基金 .

18.2018 .血清性激素及活性代谢物质谱检测新技术研究及多指标联合诊断多囊卵巢综合征的模型构建.北京大学第三医院.院临床重点项目孵育项目A类 .

19.2018 .卫生技术评估在药品市场准入中的应用及决策转化研究.北京大学第三医院.院临床重点项目孵育项目B类 .

20.2017 .基于群体药动学确定万古霉素在接受CVVH治疗的重症患者中的给药方案研究.北京大学第三医院.院临床重点项目（多科）培育探索项目（多科） .