摘要 为评估吃樱桃的生理作用，我们测定了10名健康女性吃樱桃后的血浆尿酸、抗氧化和炎性标记物水平。这些女性健康者的年龄为22-40岁，先空腹一晚后，吃两份樱桃(280 g)，吃樱桃前和之后的1.5、3和5小时分别收集血和尿测定指标。结果发现，吃樱桃后5小时的血浆平均血尿酸明显降低[分别为(183±15) mmol/L和(214±13) mmol/L (P < 0.05)]。 尿尿酸则明显增高，最高值在吃樱桃后的3小时，达（350±33）mmol/mmol肌酐，而吃前的基线值为（202±13）(p < 0.01)。吃后3小时的血浆crp和no浓度明显降低(p<0.01), 而血浆白蛋白和肿瘤坏死因子α无变化。樱桃中的维生素c是其唯一脱氢抗坏血酸，吃樱桃后的血浆坏血酸的增高提示果实中的脱氢坏血酸是有生物利用度的。吃樱桃后血浆尿酸降低支持樱桃有抗痛风作用，炎性指标（crp和no）有降低趋势则提示樱桃有抑制炎症通路的作用。

附原文：To assess the physiologic effects of cherry consumption, we measured plasma urate, antioxidant and inflammatory markers in 10 healthy women who consumed Bing sweet cherries. The women, age 22-40 y, consumed two servings (280 g) of cherries after an overnight fast. Blood and urine samples were taken before the cherry dose, and at 1.5, 3 and 5 h postdose. Plasma urate decreased 5 h postdose, mean +/- SEM = 183 +/- 15 micro mol/L compared with predose baseline of 214 +/- 13 micro mol/L (P < 0.05). urinary urate increased postdose, with peak excretion of 350 +/- 33 micro mol/mmol creatinine 3 h postdose compared with 202 +/- 13 at baseline (p < 0.01). plasma c-reactive protein (crp) and nitric oxide (no) concentrations had decreased marginally 3 h postdose (p < 0.1), whereas plasma albumin and tumor necrosis factor-alpha were unchanged. the vitamin c content of the cherries was solely as dehydroascorbic acid, but postdose increases in plasma ascorbic acid indicated that dehydroascorbic acid in fruits is bioavailable as vitamin c. the decrease in plasma urate after cherry consumption supports the reputed anti-gout efficacy of cherries. the trend toward decreased inflammatory indices (crp and no) adds to the in vitro evidence that compounds in cherries may inhibit inflammatory pathways.

引自：Jacob RA, et al.Consumption of cherries lowers plasma urate in healthy women. J Nutr. 2003 Jun;133(6):1826-9.