科研成果

部分发表在SCI期刊上的文章

1. Han C and Abel PW. Neuropeptide Y potentiates contraction and inhibits relaxation of rabbit coronary arteries. J Cardiovasc Pharmacol, 1987, 9:675

2. Han C, Abel PW, Minneman KP. α₁-Adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca²⁺ in smooth muscle. Nature, 1987, 329:333-335

3. Han C, Abel PW, Minneman KP. Hetrogeneity of α₁ - adrenergic receptors revealed by chlorethylclonidine. Mol Pharmacol, 1987, 32:505-510

4. Minneman KP, Han C, Abel PW. Comparison of α₁ - adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101. Mol Pharmacol, 1988,33:509-514

5. Abel PW, Han C, Noe BD and McDonald JK. Neuropeptide Y:Vasoconstrictor effects and role in cerebral vasospasm after experimental subarachnoid hemorrhage. Brain Res, 1988, 463: 250-258

6. McDonald JK, Han C, Noe BD and Abel PW. High level of NPY in rabbit cerebrospinal fluid and immunohistochemical analysis of possible sources. Brain Res, 1988, 463:259-267

7. Guo Yanhong, Chen Kuanghueih, Gao Wei, Li Qian, Chen Li, Wang Guisong, Tang Jian. Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit. Biochem Biophys Res Commun, 2007, 363:411-417

8. Abel PW and Han C. Effects of neuropeptide Y on contraction, relaxation, and membrane potential of rabbit cerebral arteries. J Cardiovasc Pharmacol, 1989, 13 :52-63

9. Han C, Wang X, Fiscus RR, Gu J, McDonalk JK. Changes in cardiac neuropeptide Y after myocardial infarction in rat. Neurosci Lett, 1989, 104:141-146

10. Han C, Wilson KM, Minneman KP. α₁-Adrenergic receptor subtypes and formation of inositol phosphates in dispersed hepatocytes and renal cells. Molecular Pharmacol, 1990, 37:903-910

11. Han C, Li J ane Minneman KP. Subtypes of α₁-adrenoceptors in rat blood vessels. Eur J Pharmacol, 1990, 190: 97-104

12. Minneman KP , Wilson KM , Han C. α₁-Adrenergic receptor subtypes : pharmacology and signal transduction. in "Adrenoceptors: structure, mechanismsfunction" ed. E. Szabaei and C.M.Bradshaq, Birkharse Verlag, Basel, 1991, PP.15-25

13. Wang X, Han C, Fiscus RR, Qi M, Jones SB. Hypotension- and endotoxin induced alterations in calcitonin hene- related peptide: modulation by dexamethasone. Circulatory Shock,1991, 34: 217-223

14. Wang X, Han C, Fiscus RR. Calcitonin gene- related peptide (CGRP) causes endothelium- dependent cyclic AMP, cyclic GMP and vasorelaxant responses inratabdominal aorta. Neuropeptides, 1991, 20:115-124

15. Fiscus RR, Zhou H, Wang X, Han C, Ali S, Joyce C, Murak F. Calcitonin generelated peptide(CGRP) – induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF). Neuropeptides，1991, 20: 133-143

16. Han C, Minneman KP. Interaction of subtype - selective antagonists with α₁-adrenergic receptor binding sites in rat tissues. Mol Pharmacol，1991,40:531-538

17. Han C, Wu J, Yang L, Chen M. The two subtypes of α₁- adrenergic receptor existing in rat heart. Chinese Science Bulletin，1991, 36:743-747

18. Minneman KP, Esbenshade TA, Han C. Subtypes of α-adrenoceptors in contraction of vascular smooth muscle. Jpn J Pharmacol，1992, 58 :128-134

19. Han C, Esbenshade TA, Minneman KP. Subtypes of α₁-adrenoceptors in DDT₁MF-2 and BC3H-1 clonal cell lines. Eur J Pharmacol, 1992, 226 :141-148

20. Esbenshade TA, Han C, Theroux TL, Minneman KP. Coexisting β₁ - and atypical β-adrenergic receptors cause redundant increases in cyclic AMP in human neuroblastoma cells. Mol Pharmacol，1992, 42 :753-759

21. Wang X, Jones S. B, Zhou Z, Han C, and Fiscus R.R. Calcitonin gene -related peptide (CGRP) and neuropeptide Y (NPY) levels are elevated in plasma and depleted in blood vessels during endotoxin shock in the rat. Cir Shock, 1992, 36:21-30

22. Yu G, Han Q, Chen M. A new α₁-adrenergic receptor subtype with lone affinity for 5-methyl- urapidil but insensitine to chlorethylclonidine. Acta Pharmacol Sin, 1993,14:492-495

23. Esbenshade TA, Han C, Murphy TJ, Minneman KP. Comparison of α₁ -adrenergic receptor subtypes and signal transduction in SK- N- MC and NB41A3 neuronal cell lines. Mol Pharmacol, 1993, 44:76-86

24. Esbenshade TA, Han C, Minneman KP. [³H] prazosin does not distinguish α₁- adrenoceptor subtypes in rat tissues. Pharmacology Communications, 1993, 3:323-332

25. Xia Y, Han C. Role of K⁺ channel in neuropeptide Y-induced vasoconstriction in rabbit cerebral basilar artery. Eur J Pharmacol, 1994,255:67-72

26. Minneman KP, Theroux TL, Hollinger S, Han C, Esbenshade TA. Selectivity of agonists for cloned α₁ – adrenergic receptor subtypes. Mol Pharmacol, 1994,46 :929-936

27. Yu G, Han C. Role of α_1A-andα_1B-adrenoceptor in phenylephrine-indued positive inotropic response in isolated rat left atrium. J Cardiovas Pharmacol 1994,24 :745-751

28. Chen S, Han C. Increase of release of neuroeptide Y in vitro from platelets of spontaneously hypertensive rats. Acta Pharmacol Sin，1995,16:149-152

29. Wang X, Han C, Hones SB, Yang L, Fiscus RR. Calcitonin gene -related peptiderelease in endotoxicosis may be mediated by prostaglandins. Shock 1995, 3:34-39

30. Chen S, Han C. Thrombin-induced neuropeptide Y secretion from rat platelets. Acta Pharmacol Sin，1995, 16:360-365

31. Dong E, Chen M, Han C. Differences of desensitization and hypersensitization between α_1A- and α_1B- adreneceptors in rat blood vessels. Acta Pharmacol Sin, 1995, 16:481-484

32. Yu G, Chen M, Han C. Alterations of subtypes of cardiac adrenoceptors in old rat. Acta Pharmacol Sin，1995, 16: 452 -454

33. Han C, Minneman KP. ³H-tamsulosin binding to cloned α₁-adrenergic receptorsubtypes expressed in human embryonic kidney 293 cells : antaginist potencies and sensitivity to alkylating agents. Pharmacol Comm，1995, 5: 117-126

34. Lu Z, Qu P, Xu K, Han C. β-Adreneceptors in endothelium of rabbit coronary artery and alteration in atherosclerosio. Biol Signals，1995,4:150-159

35. Han C, Yu G, Zhang Y, Xu K, Qu P, Dong E. Alterations of α₁-adrenoceptor subtypes in the hearts of thyroxine-treated rats. Eur J Pharmacol, 1995,294:593-599

36. Han C, Yu G. Selectivity of naftopiolil for subtypes of α₁-adrenoceptor. Pharmacol Comm，1996,7:125-130

37. Wang X, Tang Y., Fiscus R. R, Han C. Rapidnitric oxide- and prostaglandin- dependent release of calcitonin gene –related peptide (CGRP) triggered by endotoxin in rat mesenteric arterial bed. Br. J. Pharmacol，1996,118:2164-2170

38. Kaiming Xu, Chide Han. Quantification of mRNAs for three α₁ -adrdnoceptor subtypes in rat aorta by solution hybridization. Life Sci, 1996,59:343-347

39. Chide Han, Zhizheng Lu, Xuan Wei, and Guozhang jin. Tetrahydroprotoberberine analogs antagonize α₁- adrenoceptors and inhibit mobilization of intracellular calcium. Drug development research, 1996,39: 191- 196

40. Jie Chen, Li-Fan Zhang, Chide Han, GengSheng Yu, Jin Ma. Modulation of myocardial α₁-but not β- adrenoceptors after 90-day tail-suspension. Journal of Gravitational Physioloh, 1996,3:57-62

41. Zhang Y, Xu K, Han C. Alterations of cardiac a₁-adrenoceptor subtypes in hypothyroid rats. Clin Exper Pharmacol Physiol, 1997, 24:481-486.

42. Zhang P, Han QD, Zhang YY, Xu KM, Tian B, Lu ZZ, Guo JX, Chen MZ. Alterations of cardiac and lymphocyte b-adrenoceptors in rat with chronic heart failure. Science in China (Series C) ,1997, 40:22-26

43. Ipsen M, Zhang Y, Dragsted N, Han C, Mulvany MJ. The antipsychotic drug sertindole is a specific inhibitor of a_1A-adrenoceptors in rat mesenteric small arteries. Eur J Pharmacol, 1997, 336:29-35.

44. Chen H, Zhang Y, Han C. Chimeric dopamine D₂/angiotensin AT₁ receptors: role of the length of third intracellular loop of D₂ receptors in conferring specificity of receptor binding and G-protein coupling. Acta Pharmacol Sin, 1997,18:209-213.

45. Kaiming Xu, Fai Tang and Chide Han. Alteration of mRNA levels of α₁ -adrenoceptor subtypes with maturation and ageing in different rat blood vessels. Clinical and Experimental. Pharmacology and Toxicology, 1997, 24:415-417

46. Tang Y, Han C and Wang X. The role of calcium in endotoxin-induced release of calcitonin gene- related peptide (CGRP) from rat spinal cord. Science in China 1997, 40:437-442

47. Tang Y, Han C, Fiscus RR, Wang X. Increase of calcitonin gene-related peiptide (CGRP) release and mRNA

48. levels in endotoxic rats. Shock, 1997, 7:225-229.

49. Chen H, Lu Z, Wei H, Han C. Induction of ICE and inhibition of c-fos, jun D and zif 268 in 12- month old spontaneously hypertensive rats. Life Sci, 1997,61:27-31.

50. Zhu WZ, ZhangYY, Han QD. Characterization of subtype of a₁-adrenoceptor mediating vasoconstriction in perfused rat hinb limb. Eur J Pharmacol, 1997, 329:55-61

51. Tao L, Guan YY, He HH, Han C, ZhangYY, Sun JJ. Comparison of the Ca²⁺ movement by activation of a₁-adrenoceptor subtypes in HEK 293 cells. Life Sci, 1997, 61:2127-2136

52. Xu KM, Han QD, Tian B, Zhang YY. Agonist-induced down-regulation of a_1B-adrenoceptor in HEK 293 cells transfected with a_1B cDNA. Science in China (Series C), 1998, 41:309-314

53. Xu K, Lu Z, Wei H, Zhang Y, Han C. Alteration of a₁-adrenoceptor subtypes in aortas of 12-month- old spontaneously hypertensive rats. Eur J Pharmacol, 1998, 344:31-36

54. Wei-zhong Zhu, Chiu-yin Kwan, Chide Han. Ca⁺²-dependence of vasoconstriction mediated by a_1A- adrenoceptors in perfused rat hindlimb: a pharmacological approach. Life Sci, 1998, 63: 89-94

55. Zhu Wei-Zhong, Han Qi-De. Tyrosine kinases participate in a_1A-adrenoceptor-mediated vasoconstriction in perfused rat hindlimb. Acta Pharmacol Sin, 1998, 19: 473-477

56. Yan M, Zhang Y, Du X, Han C. Functional assessment of a₁-adrenoceptor subtypes in porcine coronary artery. Clin Exper Pharmacol Physiol，1998, 25:682-685

57. Yan M, Lu Z, Du X, and Han C. Effects of Micromolar Concentratons of Mn, Mo, and Si on a₁- adrenoceptor- Mediated Contraction in Porcine Coronary Artery. Biological Trace Element Research. 1998, 64:75-87

58. Xian Wang, Liyu Xing, Yutong Xing, Yueming Tang, Chide Han. Identification and characterization of immunoreactive calcitonin gene-related peptide from lymphocytes of the rat. Journal of Neuroimmunology, 1999, 94:95-102

59. Chen Bei, He Yong, Xiang Jizhou, Guo Lianjun and Han Qide. An animal and clinical study on the change of neuropeptide Y release evoked by electrical stimulation and myocardial ischemia. Chin Med J, 1999, 112: 410-413

60. Wei Hong, Lu Zhizhen, Zhang Youyi and Han Qide. Analysis of a₁-adrenoceptor subtypes in neonatal rat heart. Chinese Science Bulletin , 1999, 44: 1098-1101

61. Zhu W, Zhang Y, Han C: Characterization of subtype of a₁-adrenoceptor mediating vasoconstriction in perfused rat mesenteric vascular bed. Acta Pharmcol Sin, 1999, 20:151-156

62. Han Qide. Physiological and pathophysiological significance of co-existence of three subtypes of a₁- adrenoceptor in heart and blood vessels. Chin Med J, 1999, 112:950-955

63. Zhu Weizhong, Gao Benbo, Li Hewang, Zhang Youyi, Han Qi-de. Tyrosine Kinase participates in a_1A-Adrenoceptor-mediated increase of intracellular calcium in human embryo kidney293 cells. Acta Pharmacol Sin, 1999, 20: 1025-1030

64. Youyi Zhang, Kaiming Xu, Chide Han. a₁-Adrenoceptor Subtypes Mediating Inotropic Responses in Rat Heart. J Pharmacol Exp Ther, 1999, 291:829-836

65. Y Tang, C. Han, X Wang. Role of nitric oxide and prostaglandins in the potentiating effects of calcitonin gene-related peptide on lipopolysaccharide-induced interleukin-6 release from mouse peritoneal macrophages. Immunology, 1999, 96:171-175

66. Lei Beilei and Han Qide. Different patterns of agonist-induced modulation of a_1B-adrenoceptor density at different initial expression levels. Chinese Science Bulletin, 2000, 45: 1575-1578

67. Gao Benbo, Lei Beilei, Zhang Youyi and Han Qide. Cell proliferation and Ca²⁺-calmodulin dependent protein kinase activation mediated by a_1A- and a_1B-adrenergic receptor in HEK293 cells. Acta Pharmacol Sin, 2000, 21: 55-59

68. Beilei Lei, Youyi Zhang, Chide Han. Sustained norepinephrine stimulation induces different regulation of expression in three a₁-adrenoceptor subtypes. Life Sci, 2001, 69: 301-308

69. Lei BL, Zhang YY, Han QD. Changes of mRNA expression induced by sustained norepiniphrine stimulation are different in subtypes of a1-adrenoceptor in HEK293 cells. Clin Exp Pharmacol Physiol, 2002, 29: 1084-90

70. Xu Qi, Zhu Weizhong, Lu Zhizhen, Zhang Youyi , Han Qide. a1A-adrenergic receptor mediated pressor ressponese to phenylephrine in anesthetized rat. Science in China Ser. C Life Sci, 2004, 47: 59-65

71. Song Y, Huang Y, Han QD and ZHANG YY. Characterization of cAMP accumulation mediated by three a₁-

72. adrenoceptor subtypes in HEK293 cells. Acta Pharmacol Sin, 2003, 24: 549-554

73. Han JL, Zhang YY, Lu ZZ, Mao JM, Chen MZ, Han QD. Functional a₁-Adrenergic Receptor Subtypes in Human Right Gastroepiploic Artery. Acta Pharmacol Sin, 2003; 24: 327-331

74. Feng Yin, Ping Li, Ming Zheng, Li Chen, Qi Xu, Kai Chen, Yong-yu Wang, You-yi Zhanag, Chide Han. Intereleukin-6 Family of Cytokines Mediates Isoproterenol-Induced Delayed STAT3 Activation in Mouse Heart. J Biol Chem, 2003, 23:21070-21075

75. P.Li, J.Li, R. Hou, C. Han, Y. Zhang. Gene expression profile of cardiomyocytes in hypertrophic heart induced by continuous norepinephrine infusion in thes rats. CMLS, Cell. Mol. Life Sci. 2003,60: 2200-2209

76. Jinliang Li, Ping Li, Xinheng Feng, Zhaoping Li, Rong Hou, Chide Han and Youyi Zhang. Effects of losartan on pressure overload-induced cardiac gene expression profiling in rats. Clin Exp Pharmacol Physiol, 2003, 30: 827-832

77. Yongyu Wang, Rong Hou, Ping Li, Jinliang Li, Jie Yan, Chide Han and Youyi Zhang. Gene Expression Profiles in Response to thes Activation of Adrenoceptos in A7R5 Aortic Smooth Muscle Cells. Clin Exp Pharmacol Physiol, 2004, 31: 602-607

78. Yongzhen Zhang, Jie Yan, Kai Chen, Yao Song, Zhizhen Lu, Mingzhe Chen, Chide Han and Youyi Zhang. Different Roles of a₁-adrenoceptor Subtypes in Mediating Cardiomyocyte Protein Synthesis in Neonatal Rats. Clin Exp Pharmacol Physiol 2004, 31: 626-633

79. Tan Zhang, Qi Xu, Feng-rong Chen, Qi-de Ham, You-yi Zhang. Yeast Two-hybrid screening for protein that interact with a₁-adrenergic receptor. Acta Pharmacoi Sin, 2004, 25: 1471-1478

80. Yao Song, Yunfang LI, Erdan Dong, Qide Han, Youyi Zhang. Ca2+ participates in a1B- adrenoceptor- mediated cAMP response in HEK293 Cells. Acta Phamacol Sin, 2005, 26: 77-84

81. Wenqiang Liao, Shuyi Wang, Chide Han and Youyi Zhang. 14-3-3 Protein regulate glycogen synthase 3b phosphorylation and inhibit cardiomyocyte hypertrophy. FEBS Journal(原EJB), 2005, 272: 1845-1854

82. Wang Yu, Yuan Bingxiang, Deng Xiuling, He Langchong, Zhang Youyi, Han Qide. The preparation of HEK293 a_1A or HEK293 a_1B cell membrane stationary phase and the chromatographic affinity study of ligands of a₁ adrenoceptor. Analitical Biochemistry, 2005,339:198-205

83. Xu Ning, Xu Ming, Zhang Youyi. Optical detection of single molecules in living cells. Acta Physiologica, 2005, 57: 271-277

84. Jianhai Du, Wenqiang Liao, Yongyu Wang, Chide Han, Youyi Zhang. Inhibitory effect of 14-3-3 proteins on serum –induced proliferation of cardiac fibroblasts. Eur J Cell Biol 2005, 84:843-852

85. Jian Wang, Ning Xu, Xinheng Feng, Ning Hou, JiShuai Zhang, Xuan Cheng, Youyi Zhang and Xiao Yang. Targeted Disruption of Smad4 in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure. Circulation Res, 2005, 97: 821-828

86. Jianhai Du, Ning Xu, Yao Song, Ming Xu, Zhizhen Lu, Chide Han, Youyi Zhang. AICAR stimulates IL-6 production via p38 MAPK in cardiac fibroblasts in adult mice: A possible role for AMPK. Biochem Biophys Res Commun, 2005, 337:1139-1144

87. Feng Yin, Yongyu Wang, Jianhai Du, Chun Li, Zhizhen Lu, Chide Han, Youyi Zhang. Noncanonical cAMP pathyway and p38 MAPK mediate b₂-adrenergic receptor-induced IL-6 production in neonatal mouse cardiac fibroblasts. J Mol Cardiol, 2006, 40:384-393

88. Z Huang, LL Wu, Y Y Zhang, Y Gao, and GY Yu. Functional a1-Adreniceptor Subtypes in Human Submandibular Glands. Journal of Dental Research (Featuring Critical Review in Oral Biology & Medicine), 2006.3, 85:251-256

89. Li Zijian, Liu Ning, Liu Zhiqiang, Liu Shuying, Han Qide and Zhang Youyi. Differential Proteomic Analysis of neonatal Cardiomyocytes in Responsse to b-Adrenergic Receptor Stimulation. Chem. Res. Chinese U，2006, 22: 319-323

90. Qi Xu, Ning Xu, Tan Zhang, Hui Zhang, Zijian Li, Feng Yin, Zhizhen Lu, Qide Han, and Youyi Zhang. Mammalian Tolloid Alters Subcellular Localization, Inte-rnalization, and Signaling of a1a-Adrenergic Receptors. Mol Pharmacol, 2006, 70: 532-541

91. Ruiping Xiao, Weizhong Zhu, Ming Zheng, Chunmei Cao, Youyi zhang, Edward G. Lakatta and Qide Han. Subtype-Specific a1- and b-Adrenoceptor Signaling in the Heart. TiPS, 2006, 27: 330-337 (TRENDS in pharmacological Sciences)

92. Ming Xu, Yinghua Guan, Ning Xu, Zhangyi Liang, Zhizhen Lu,Qide Han, Xinsheng Zhao, and Youyi Zhang. Dynamic Behaviors of a1B-Adrenergic Receptor in Living Cells. Solid Phenomena , 2007, 121-123: 771-775

93. Kaizheng Gong, Hui Zhang, Jianhai Du, Youyi Zhang. Crosstalk between signaling pathway of adrenoreceptors and signal transducers and activators of transcription 3 (STAT3) in heart. Acta Pharmacol Sin, 2007, 28:153-165

94. Ming Xu, Peng Zhou, Shiming Xu, Yin Liu, Xinheng Feng, Shuhua Bai, Yan Bai, Xuemei Hao, Qide han, Youyi Zhang, Shiqiang Wang. Intermolecular Failure of L-type Ca2+ Channel and Ryanodine Receptor Signaling in hypertrophy. PLoS biology, 2007, 5:203-211(e21)

95. Shuyi Wang, Yao Song, Ming Xu, Qihua He, Qide Han, Youyi Zhang. Internalization and distribution of three a₁-adrenoceptor subtypes in HEK293A cells before and after agonist stimulation. Acta Pharmacol Sin, 2007, 28: 359-366

96. Ning XU, Zhangyi Liang, Ming XU, Yinghua GUAN, Qihua HE, Qide Han, Xinsheng Zhao, Youyi Zhang. Real-time detection of a1A-AR movement stimulated by phenylephrine in single living cells. Acta pharmacol Sin, 2007, 28:796-802

97. Xu Ming, Zhao Yanting, Hao Tianpao, Song Yao, Lu Zhizhen, Han Qide, Wang Shiqiang, Zhang Youyi.a1-adrenergic receptors activate AMP-activated protein kinase in rat hearts. Acta Physiol Sin, 2007, 59: 175-182

98. Yinghua Guan, Ming Xu , Zhangyi Liang, Ning Xu, Zhizhen Lu, Qide Han, Youyi Zhang, Xin Sheng Zhao. Heterogeneous transportation of a1B-adrenoceptor living cells. Biophysical Chemistry, 2007, 127: 149-154

99. Liang ZY, Xu N, Guan YH, Xu M, He QH, Han QD, Zhang YY, Zhao XS. The transport of a1A-AR-adrenergic receptor with 33-nm step size in live cells. Biochem Biophys Res Commun, 2007, 353: 231-237

100. Du JH, Guan TJ, Zhang H, Xiao H, Han QD, Zhang YY. Phenylarsine oxide inhibited beta- adrenergic receptor-mediated IL-6 secretion: inhibition of cAMP accumulation and CREB activation in cardiac fibroblasts. Biochem Biophys Res Commun, 2007, 352: 744-749

101. Dali Luo, Jian Gao, Lin-lin Fan, Yu Tang, Youyi Zhang, Qide Han. Receptor subtype involved in a1-adrenergic receptor-mediated Ca2+ signaling in cardiomyocytes. Acta Phamacol Sin, 2007, 28: 968-974

102. Lei Qin, Jianyong Huang, Chunyang Xiong, Youyi Zhang, Jing Fang. Dynamical stress characterization and energy evaluation of single cardiac myocyte actuating on flexible substrate. Biochem Biophys Res Commun, 2007, 360: 352-356

103. Tongju Guan , Feng-jin Qin, Jianhai Du , Li Geng, Youyi Zhang Min Li. AICAR inhibited proliferation, induced S-phase arrest and promoted apoptosis in CaSki cells. Acta Pharmacol Sin, 2007, 28: 1984-1990

104. Zhangyi Liang, Ning Xu, Yinghua Guan, Youyi Zhang, Xinsheng Zhao. Mode of Myosin Transportation in Living Cell Studied by Single Particle Tracking. ChinJ Chem Phys, 2007, 20: 445-448

105. Han Xiao, Youyi Zhang. Frontiers in Research Review: Better Understanding of Disease Mechanism: From Phenotype to Genotype- Understanding the role of transforming growth factor-b signalling in the heart: overview of studies using genetic mouse models. Clin Exp Pharmacol Physiol, 2008, 35: 335-341

106. Jianhai Du, Tongju Guan, Hui Zhang, Yi Xia, Fei Liu, Youyi Zhang. Inhibitory crosstalk between ERK and AMPK in the growth 3 and proliferation of cardiac fibroblasts. Biochem Biophys Res Commun, 2008, 368:402-407

107. Hui Zhang, Wei Feng, Wenqiang Liao, Xiaowei Ma, Qide Han and Youyi Zhang. The gp130/STAT3 signaling pathway mediates b-adrenergic receptor-induced atrial natriuretic factor expression in cardiomyocytes. The FEBS Journal, 2008, 275:3590-3597

108. Lingyun Jia, Mingjiang Xu, Wei Zhen, Xun Shen, Yi Zhu, Wang Wang and Xian Wang. Nivel anti-oxidative role of calreticulin in protecting A549 human type II alveolar epithelial cells against hypoxic injury. Am J Physiol 2008, 294:C47-C55.

109. Gong K, Li Z, Xu M, Du J, Lv Z, Zhang Y. A novel PKA-independent, beta -arrestin-1-dependent signaling pathway for p38 mitogen-activated protein kinase activation by beta 2-adrenergic receptors. J Biol Chem, 2008, Aug 4. [Epub ahead of print]

110. Guo Yanhong, Chen Kuanghueih, Gao Wei, Li Qian, Chen Li, Wang Guisong, Tang Jian. Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit. Biochem Biophys Res Commun, 2007, 363:411-417.

111. Xiaomei Guo; Kuang-Hueih Chen; Yanhong Guo; Hua Liao; Jian Tang and Ruiping Xiao. Mitofusin 2 Triggers Vascular Smooth Muscle Cell Apoptosis via Mitochondrial Death Pathway. Circ Res. 2007, 101: 1113-22.

112. Lina Wu, Zhixin Li, Yingmei Zhang, Pei Zhang, Xiaohui Zhu, Jing Huang, Teng Ma, Tian Lu, Quansheng Song, Qian Li, Yanhong Guo, Jian Tang, Dalong Ma, Kuang-Hueih Chen and Xiaoyan Qiu. Adenovirus-expressed human hyperplasia suppressor gene induces apoptosis in cancer cells. Mol Cancer Ther, 2008, 7:222-32

113. Hua Yan, Yanhong Guo, Peng Zhang, Lingyun Zu, Xiaoyan Dong, Li Chen, Jianwei Tian, Xiaolong Fan, Nanping Wang, Xiaobing Wu and Wei Gao. Superior neovascularization and muscle regeneration in ischemic skeletal muscles following VEGF gene transfer by rAAV1 pseudotyped vectors. Biochem Biophys Res Commun, 2005, 336:287-98.

114. Kuang-Hueih Chen, Xiaomei Guo, Dalong Ma, Yanhong Guo, Qian Li, Dongmei Yang, Pengfei Li, Xiaoyan Qiu, Shaojun Wen, Rui-Ping Xiao & Jian Tang. Dysregulation of HSG triggers vascular proliferative disorders. Nat Cell Biol, 2004, 6: 872-83.

115. Zhang Guohua, Tan xiaofan, Shen Dong, Zhao Shuyuan, Shi Yanyi, Jin caike, Sun Weigu, Guo Yanhong, Chen Kuanghui, Tang Jian. Gene expression and antitumor effect following in electroporation delivery of human interferon alpha gene. Acta Pharmacol Sin, 2003, 24:891-896.

116. Yanhong Guo, Wei Gao, Qian Li, Pengfei Li, Pengying Yao and Kuanghueih Chen. Tissue inhibitor of metalloproteinases-4 suppresses vascular smooth muscle cell migration and induces cell apoptosis. Life Sci, 2004, 75:2483-2493.

117. Jiang J, Jiang N, Gao W, Zhu JJ, Guo YH, Shen D, Chen GH, Tang J. Augmentation of revascularization and prevention of plasma leakage by angiopoietin-1 and vascular endothelial growth factor co-transfection in rats with experimental limb ischaemia. Acta Cardiol, 2006, 61: 145-153.

118. Wang G, Dai J, Mao J, Wang X. Folic acid reverses hyper-responsiveness of LPS-induced chemokine secretion from monocytes in patients with hyperhomocysteinemia. Atherosclerosis, 2005, 179:395-402.

119. Wang G, Wei J, Guan Y, Mao J, Wang X. PPAR-γ Agonist rosiglitazone reduces clinical inflammatory responses in type 2 diabetes with coronary artery disease after coronary Angioplasty. Metabolism, 2005, 54:590-597

120. Wang G，Mao J, Wang X. Effect of homocysteine on plaque formation of acute coronary syndromes patients and the mechanisms of oxidative stress. Chinese Medical Journal, 2004, 117:1650-1654.

121. Yu J , Jin N, Wang G, Wang X, Zhang F^, , Mao J. PPAR-γ agonist improved arterial stiffness in type 2 diabetes patients with coronary artery disease. Metabolism, 2007, 56:1396-1401

122. Sun W， Wang G，Zhang Z, Zeng X, Wang X. Chemokine. Rantes is upregulated in monocytes from patients with hyperhomocysteinemia. Acta Pharmacol Sin, 2005, 26:1317-1321.

123. Wang X, Wang G, Mao J. Enhanced chemokine of secretion monocytes in response to lipopolysaccharide challenge in hyperhomocysteinemic patients. Circulation, 2003, 108:Ⅳ65 (abstract). Oral presentation in AHA conference , 2003.

124. Haiyan Li, Koji Tanaka, Hitoshi Anzai, Brandy Oeser, Dominic Lai, Jon A. Kobashigawa, and Jonathan M. Tobis. Influence of pre-existing donor atherosclerosis on the development of cardiac allograft vasculopathy and outcomes in heart transplant recipients. J Am Coll Cardiol. 2006, 47:2470-2476.

125. Haiyan Li, Koji Tanaka, Brandy Oeser, Jon A. Kobashigawa and Jonathan M. Tobis Vascular remodelling after cardiac transplantation: a 3-year serial intravascular ultrasound study. Eur Heart J. 2006, 27:1671-1677

126. Li HY, Tanaka K, Chhabra A, et al. Vascular remodeling 1 Year After Cardiac Transplantation. J Heart Lung Transplant, 2007, 26:56-62

127. Sun Lijie, Cui Ming, Wang Zuoyan, Feng Xinheng, Mao Jieming, Chen Ping, Ma Kangtao, Chen Fengrong, Zhou Chunyan. Mesenchymal stem cells modified with angiopoietin-1 improve remodeling in a rat model of Acute Myocardial Infaction. Biochem Biophys Res Commun, 2007, 357: 779-784

128. Jie Yu, Nan Jin, Guang Wang, Fuchu Zhang, Jieming mao, xian wang. Peroxisome proliferators-activated receptorγagonist improves arterial stiffness in patients with type 2 diabetes mellitus and coronary artery disease. Metabolism Clinical and Experimental.2007, 56.1396-1401.

129. Zhang SH, Zhang P, Guo JX, et al. Enhanced cytoprotection and angiogenesis by bone marrow cell transplantation may contribute to improved ischemic myocardial function. Euro J Cardio-Thoracic Surgery 2004, 25:188-195

130. Zhang SH, Guo JX, Zhang P, et al. Long-term effects of bone marrow mononuclear cell transplantation on left ventricular function and remodeling in rats. Life Sciences 2004; 74:2853-2864

131. Lei L, Guo JX, Liu DG, et al. Histochemical study of transmyocardial laser channel in dogs. Chinese Medical Journal, 2007, 114: 902-905

132. Jie Yu, Nan Jin, Guang Wang, Fuchu Zhang, Jieming mao, xian wang. Peroxisome proliferators-activated receptorγagonist improves arterial stiffness in patients with type 2 diabetes mellitus and coronary artery disease. Metabolism Clinical and Experimental.2007, 56: 1396-1401.

133. Odgerel Tumur, Han Jiang-li, Yang Chi-sun, Mao Jie-ming. The relationship between sex hormones and extent of coronary artery disease in postmenopausal women. Chinese Medical Journal, 2007,120: 71-73

134. Wang ZY, Cui Min,sun LJ, Jia ZQ, Bai Yun, Mao KT, Chen FR, Zhou CY. Angiopoietin-1 protect H9C2 cells from apoptosis through Akt signaling. Biochem Biophys Res Commun, 2007, 359: 685-690