专家介绍

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李冬梅

  • 专业职称:教授,主任医师
  • 擅长:专门从事眼整形及美容外科临床及科研工作,在临床工作中积累了数万例手术经验(年手术量1000余例),对眼睑、眼窝和眼眶整形有较深入的研究。擅长各类眼部整形及美容手术、先天及获得性眼部畸形的修复与重建。目前在国内外眼整形领域成就斐然,享有盛誉,是目前国内乃至世界一流的眼整形专家。每年受邀于国内外会议专题演讲。在眼整形领域进行多项开创性手术:率先开展了先天性小眼球及无眼球患儿的眼眶发育干预治疗及评估,采用定时点的眼睑结膜囊扩张术,眼眶发育干预治疗,达到较为满意效果。开展先天眶面畸形整复及复杂眶窝畸形整复并获科技进步奖。

个人介绍

科研工作

承担十余项国家及省部级课题。目前在研课题:国自然面上一项,北京市项目一项。主编主译9部专著,发表第一及通讯作者中英文文章100余篇。专利4项,转化一项,北京市科技成果三等奖(第一作者)

学术兼职

亚太眼整形学会 主席(APSOPRS)

亚太眼科学会 女医师分会 常务理事(WIO)

国际甲状腺相关眼病学会 常务理事(ITED)

中华医学会眼科分会眼整形眼眶病学组副组长

中国女医师学会眼科专委会 常委

北京眼科学会眼整形眼眶病专委会主委

《中华眼科杂志》编委

《亚太眼科杂志APJO》(IF 4.56)编委

获奖情况

2017年及2021年,亚太眼科学会杰出成就奖

2019年,亚太眼科学会卓越服务奖

2020年,“第四届国之名医-卓越建树”荣誉称号

多次获得首都医科大学优秀教师奖及同仁医院优秀中层干部奖

论文

1: Zhang L, Hou Z, Li Y, Li D. Combined Surgical Strategies Adjusted to ClinicalEvaluations for Severe Upper Eyelid Cicatricial Entropion and Trichiasis. JCraniofac Surg. 2023 Jan 13. doi: 10.1097/SCS.0000000000009170. Epub ahead ofprint. PMID: 36635852.

2: Ma L, Li Y, Zhang H, Li L, Deng G, Xu J, Li D. Abnormalities of thecontralateral eye in unilateral congenital anophthalmic or blind microphthalmicpatients. J AAPOS. 2022 Dec 21:S1091-8531(22)00794-7. doi:10.1016/j.jaapos.2022.11.011. Epub ahead of print. PMID: 36563895.

3: Shi TT, Zhao RX, Xin Z, Hou ZJ, Wang H, Xie RR, Li DM, Yang JK. Tear-derivedexosomal biomarkers of Graves' ophthalmopathy. Front Immunol. 2022 Dec6;13:1088606. doi: 10.3389/fimmu.2022.1088606. PMID: 36561758; PMCID:PMC9763563.

4: Ma L, Hui S, Li Y, Hou Z, Liu Z, Chang Q, Zhang H, Li D. DifferentCharacteristics of Orbital Soft Tissue Expansion in Graves Orbitopathy:Extraocular Muscle Expansion is Correlated to Disease Activity While Fat TissueVolume With Duration. J Craniofac Surg. 2022 Nov-Dec 01;33(8):2354-2359. doi:10.1097/SCS.0000000000008751. Epub 2022 Jul 26. PMID: 35882057.

5: Luo L, Wen H, Gao L, Li R, Wang S, Wang Z, Li D. Morphological brain changesbetween active and inactive phases of thyroid-associated ophthalmopathy: Avoxel-based morphometry study. Brain Res. 2022 Sep 1;1790:147989. doi:10.1016/j.brainres.2022.147989. Epub 2022 Jun 20. PMID: 35738426.

6: Luo L, Li D, Gao L, Wang W. Retinal nerve fiber layer and ganglion cellcomplex thickness as a diagnostic tool in early stage dysthyroid opticneuropathy. Eur J Ophthalmol. 2022 Sep;32(5):3082-3091. doi:10.1177/11206721211062030. Epub 2021 Dec 7. PMID: 34873954.

7: Wang M, Zhang H, Dong L, Li Y, Hou Z, Li D. Using the Random Forest Algorithmto Detect the Activity of Graves Orbitopathy. J Craniofac Surg. 2022 Aug 23.doi: 10.1097/SCS.0000000000008946. Epub ahead of print. PMID: 35996213.

8: Qu X, Ding J, Wang Q, Cui J, Dong J, Guo J, Li T, Xie L, Li D, Xian J. Effectof the long-term lack of half visual inputs on the white matter microstructurein congenital monocular blindness. Brain Res. 2022 Apr 15;1781:147832. doi:10.1016/j.brainres.2022.147832. Epub 2022 Feb 10. PMID: 35151655.

9: Ding J, Hou Z, Li D. Bidirectional tightening of the anterior lamella forinvolutional lower eyelid entropion. Can J Ophthalmol. 2022 Apr5:S0008-4182(22)00093-X. doi: 10.1016/j.jcjo.2022.03.005. Epub ahead of print.PMID: 35395213.

10: Zhang J, Hou Z, Li Y, Xian J, Chang Q, Li D. Orbital Volume and Axial LengthDevelopment in Individuals Ages 12 to 60 Years With Congenital Microphthalmia: ARetrospective Cohort Study. J Craniofac Surg. 2022 Mar-Apr 01;33(2):e161-e165.doi: 10.1097/SCS.0000000000008197. PMID: 35075050.

11: Ding J, Qu X, Cui J, Dong J, Guo J, Xian J, Li D. Altered Spontaneous BrainActivity and Network Property in Patients With Congenital Monocular Blindness.Front Neurol. 2022 Feb 24;13:789655. doi: 10.3389/fneur.2022.789655. PMID:35280267; PMCID: PMC8907119.

12: Gao Y, Chang Q, Li Y, Zhang H, Hou Z, Zhang Z, Li Z, Li D. Correlationbetween extent of lacrimal gland prolapse and clinical features of thyroid-associated ophthalmopathy: a retrospective observational study. BMC Ophthalmol.2022 Feb 10;22(1):66. doi: 10.1186/s12886-022-02270-9. PMID: 35144579; PMCID:PMC8832675.

13: Yuan B, Aziz MRF, Li S, Wu J, Li D, Li RK. An electro-spun tri-componentpolymer biomaterial with optoelectronic properties for neuronal differentiation.Acta Biomater. 2022 Feb;139:82-90. doi: 10.1016/j.actbio.2021.05.036. Epub 2021May 31. PMID: 34082104.

14: Song D, Zhang J, Yuan B, Rong Q, Li D. A Finite Element Analysis Model isSuitable for Biomechanical Analysis of Orbital Development. J Craniofac Surg.2021 Oct 1;32(7):2546-2550. doi: 10.1097/SCS.0000000000007558. PMID: 34705364.

15: Zhou J, Ding J, Li D. Blepharochalasis: clinical and epidemiologicalcharacteristics, surgical strategy and prognosis-- a retrospective cohort studywith 93 cases. BMC Ophthalmol. 2021 Aug 28;21(1):313. doi:10.1186/s12886-021-02049-4. PMID: 34454463; PMCID: PMC8399824.

16: Yang GR, Li D, Xie Z. Association of obesity with diabetic retinopathy in USadults with diabetes in a national survey. Endocr Connect. 2021 Jun30;10(7):725-730. doi: 10.1530/EC-21-0172. PMID: 34114968; PMCID: PMC8284949.

17: Yuan B, Jiang X, Liu Y, Dong J, Li D. Three-dimensional periorbitalasymmetry assessment of congenital microphthalmia children with a structuredlight 3D scanning system. J Craniomaxillofac Surg. 2021 Mar;49(3):206-214. doi:10.1016/j.jcms.2020.12.016. Epub 2021 Jan 12. PMID: 33487550.

18: Ding J, Xu Y, Yuan B, Li D. Management of blepharospasm and blepharophimosisassociated with Schwartz-Jampel syndrome. J AAPOS. 2021 Feb;25(1):54-56. doi:10.1016/j.jaapos.2020.10.009. Epub 2021 Feb 16. PMID: 33601038.

19: Yang GR, Li D, Li L. Comparison of Coronary Heart Disease and Stroke inAssociation with Diabetic Retinopathy in Adults with Diabetes Using a NationalSurvey. Diabetes Metab Syndr Obes. 2020 Dec 23;13:5079-5084. doi:10.2147/DMSO.S292934. PMID: 33380817; PMCID: PMC7767698.

20: Sun H, Ding JW, Li DM, Wang NL. Comparison of Hasner valvulotomy outcomes inpediatric and adult patients: does age matter? Chin Med J (Engl). 2020 Oct20;133(20):2422-2428. doi: 10.1097/CM9.0000000000001128. PMID: 32960846; PMCID:PMC7575182.

21: Li Y, Hou Z, Ding J, Cui Y, Qin B, Li D. Distinguishing risk factors betweencongenital anophthalmia and microphthalmia using multivariable logisticregression. Ann Transl Med. 2020 Jun;8(11):704. doi: 10.21037/atm.2019.12.103.PMID: 32617324; PMCID: PMC7327332.

22: Song D, Song H, Zhou L, Sun C, Wu Q, Li D. Prenatal diagnosis of bilateralcongenital microphthalmia in two fetuses from the same parents. Indian JOphthalmol. 2020 Jan;68(1):216-218. doi: 10.4103/ijo.IJO_750_19. PMID: 31856529;PMCID: PMC6951152.

23: Yang GR, Dye TD, Li D. Association between diabetes, metabolic syndrome andheart attack in US adults: a cross-sectional analysis using the Behavioral RiskFactor Surveillance System 2015. BMJ Open. 2019 Sep 13;9(9):e022990. doi:10.1136/bmjopen-2018-022990. PMID: 31519666; PMCID: PMC6747668.

24: Yang GR, Dye TD, Li D. Effects of pre-gestational diabetes mellitus andgestational diabetes mellitus on macrosomia and birth defects in Upstate NewYork. Diabetes Res Clin Pract. 2019 Sep;155:107811. doi:10.1016/j.diabres.2019.107811. Epub 2019 Aug 8. PMID: 31401151; PMCID:PMC8783133.

25: Liu Z, Xie B, Li Y, Ding J, Li D. Reconstruction strategy in isolatedcomplete Cryptophthalmos: a case series. BMC Ophthalmol. 2019 Jul 31;19(1):165.doi: 10.1186/s12886-019-1170-6. PMID: 31366340; PMCID: PMC6668120.

26: Yang GR, Yuan MX, Fu HJ, Wan G, Li D, Dye TD, Zhu LX, Xie RR, Lv YJ, ZhangJD, Du XP, Li YL, Ji Y, Li Y, Cui XL, Wang ZM, Cheng SY, Liu DY, Wang Q, Zhou L,Gao Y, Yuan SY. The Association between Metabolic Syndrome and Morbid Events inType 2 Diabetes after a 7-Year Community Management: Beijing Community DiabetesStudy 17. J Diabetes Res. 2019 Jun 12;2019:5237371. doi: 10.1155/2019/5237371.PMID: 31281851; PMCID: PMC6594276.

27: Cui Y, Li Y, Hou Z, Wang Y, Chang Q, Xian J, Li D. Management of congenitalmicrophthalmos and anophthalmos with orbital cyst. J AAPOS. 2019Apr;23(2):92.e1-92.e6. doi: 10.1016/j.jaapos.2018.10.015. Epub 2019 Mar 27.PMID: 30928365.

28: Zhang X, Wang D, Dongye M, Zhu Y, Chen C, Wang R, Long E, Liu Z, Wu X, LinD, Chen J, Lin Z, Wang J, Li W, Li Y, Li D, Lin H. Loss-of-function mutations inFREM2 disrupt eye morphogenesis. Exp Eye Res. 2019 Apr;181:302-312. doi:10.1016/j.exer.2019.02.013. Epub 2019 Feb 22. PMID: 30802441.

29: Yang GR, Dye TD, Zand MS, Fogg TT, Yuan SY, Yang JK, Li D. AssociationBetween Neck Circumference and Coronary Heart Disease: A Meta-analysis. AsianPac Isl Nurs J. 2019;4(1):34-46. doi: 10.31372/20190401.1031. PMID: 31037271;PMCID: PMC6484201.

30: Ding J, Ma X, Xin Y, Li D. Correction of lower eyelid retraction with hardpalate graft in the anophthalmic socket. Can J Ophthalmol. 2018Oct;53(5):458-461. doi: 10.1016/j.jcjo.2018.01.031. Epub 2018 Apr 2. PMID:30340710.

31: Zhang XL, Fu HJ, Yang GR, Wan G, Li D, Zhu LX, Xie RR, Lv YJ, Zhang JD, LiYL, Dai QF, Ji Y, Gao DY, Cui XL, Liu DY, Yuan SY, Yuan MX; Beijing CommunitiesDiabetes Study Group. The effects of cardiovascular risk factor combined anti-platelet therapy and the risk of cerebrovascular events in patients with T2DM inan urban community over 96-months follow-up: The Beijing communities diabetesstudy 19. Diabetes Res Clin Pract. 2018 Oct;144:236-244. doi:10.1016/j.diabres.2018.09.007. Epub 2018 Sep 13. PMID: 30218743.

32: Zhang XL, Yuan MX, Wan G, Yang GR, Li DM, Fu HJ, Zhu LX, Xie RR, Zhang JD,Lv YJ, Li YL, Du XP, Wang ZM, Cui XL, Liu DY, Gao Y, Cheng SY, Wang Q, Ji Y, LiGW, Yuan SY. The effects of AER and eGFR on outcomes of CVD in patients withT2DM in an urban community over 8 years of multifactorial treatment: the BeijingCommunities Diabetes Study 18. Ther Clin Risk Manag. 2018 Aug 31;14:1537-1545.doi: 10.2147/TCRM.S170915. PMID: 30214217; PMCID: PMC6124448.

33: Ding J, Sun H, Xin Y, Li D. Metastatic hepatocellular carcinoma mimickingacute dacryocystitis. Can J Ophthalmol. 2018 Aug;53(4):e132-e134. doi:10.1016/j.jcjo.2017.10.033. Epub 2017 Dec 11. PMID: 30119803.34: Ding J, Sun H, Li D. Persistent pediatric primary canaliculitis associatedwith congenital lacrimal fistula. Can J Ophthalmol. 2017 Oct;52(5):e161-e163.doi: 10.1016/j.jcjo.2017.03.014. Epub 2017 May 10. PMID: 28985821.

35: Luo LH, Li DM, Wang YL, Wang K, Gao LX, Li S, Yang JG, Li CL, Feng W, Guo H.Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressingAkt/NF-kB signaling pathway. Biochem Biophys Res Commun. 2017 Sep30;491(4):966-972. doi: 10.1016/j.bbrc.2017.07.144. Epub 2017 Jul 26. PMID:28756232.

36: Sun H, Li Y, Huang Q, Ding JW, Hou ZJ, Li DM. Medial Canthoplasty Combinedwith Conjunctivodacryocystorhinostomy for the Treatment of Delayed MedialTelecanthal Deformity. Chin Med J (Engl). 2017 Mar 20;130(6):698-702. doi:10.4103/0366-6999.201594. PMID: 28303853; PMCID: PMC5358420.

37: Cui Y, Zhang Y, Chang Q, Xian J, Hou Z, Li D. Digital Evaluation of OrbitalCyst Associated with Microphthalmos: Characteristics and Their Relationship withOrbital Volume. PLoS One. 2016 Jun 17;11(6):e0157819. doi:10.1371/journal.pone.0157819. PMID: 27315369; PMCID: PMC4912088.

38: Hou Z, Xian J, Chang Q, Wei W, Li D. Digital evaluation of orbitaldevelopment after self-inflating hydrogel expansion in Chinese children withcongenital microphthalmia. J Plast Reconstr Aesthet Surg. 2016 May;69(5):706-14.doi: 10.1016/j.bjps.2016.01.011. Epub 2016 Jan 19. PMID: 26923661.

39: Yan Y, Chen T, Wei W, Li D. Epiblepharon in Chinese children: relationshipswith body mass index and surgical treatment. J AAPOS. 2016 Apr;20(2):148-52.doi: 10.1016/j.jaapos.2015.12.009. PMID: 27079597.

40: Yang G, Zhang Y, Chang Q, Li D. [Measurement of orbital development inchildren from birth to 6 years of age]. Zhonghua Yan Ke Za Zhi. 2015Aug;51(8):576-80. Chinese. PMID: 26696573.

41: Ding J, Zhang Y, Li B, Xu X, Hou Z, Li D. [Repair of full-thickness lowereyelid defect following surgical excision of malignant tumor using Hughestechnique]. Zhonghua Yan Ke Za Zhi. 2014 Aug;50(8):579-83. Chinese. PMID:25385376.

42: Li D, Ding J. [Whether external dacryocystorhinostomy will be abandoned].Zhonghua Yan Ke Za Zhi. 2014 Aug;50(8):566-8. Chinese. PMID: 25385373.

43: Li D. [Pay attention to patient's visual function in oculoplastic surgeryfor congenital blepharophimosis syndrome]. Zhonghua Yan Ke Za Zhi. 2014Aug;50(8):561-2. Chinese. PMID: 25385371.

44: Hou Z, Korn BS, Ding J, Li D. Management of extensive epibulbar choristoma

associated with microphthalmos: a rare clinical entity. JAMA Ophthalmol. 2014Jun;132(6):753-5. doi: 10.1001/jamaophthalmol.2014.148. PMID: 24699722.

45: Li Y, Song H, Liu J, Li D. Use of lateral upper arm free flaps for soft-tissue reconstruction of the contracted eye socket. Plast Reconstr Surg. 2014May;133(5):675e-682e. doi: 10.1097/PRS.0000000000000133. PMID: 24776570.

46: Li DM. [Give attention to standardized management of orbital development inChinese with microphthalmos or anophthalmos]. Zhonghua Yan Ke Za Zhi. 2013Aug;49(8):676-8. Chinese. PMID: 24246803.

47: Ding J, Li B, Chen T, Hao L, Li D. Eyelid thickening and ptosis associatedwith pachydermoperiostosis: a case report and review of literature. AestheticPlast Surg. 2013 Apr;37(2):464-7. doi: 10.1007/s00266-013-0062-z. Epub 2013 Jan30. PMID: 23361957.

48: Ding J, Chen T, Hou Z, Qin Y, Hao L, Li D. Cosmetic shell fitting over asensitive cornea in mild phthisis bulbi using total conjunctival flap. AestheticPlast Surg. 2013 Apr;37(2):398-401. doi: 10.1007/s00266-012-0003-2. Epub 2013Jan 30. PMID: 23361954.

49: Hou Z, Yang Q, Chen T, Hao L, Li Y, Li D. The use of self-inflating hydrogelexpanders in pediatric patients with congenital microphthalmia in China. JAAPOS. 2012 Oct;16(5):458-63. doi: 10.1016/j.jaapos.2012.07.002. PMID: 23084385.

50: Yang G, Wang J, Chang Q, Wang Z, Geng Y, Li D. Digital evaluation of orbitaldevelopment in chinese children with congenital microphthalmia. Am J Ophthalmol.2012 Sep;154(3):601-609.e2. doi: 10.1016/j.ajo.2012.03.025. Epub 2012 May 24.PMID: 22633356.

51: Li DM. [Five-year overview of progress of oculoplastic surgery studies inChina]. Zhonghua Yan Ke Za Zhi. 2010 Oct;46(10):915-8. Chinese. PMID: 21176613.

52: Qin Y, Li D, Chen T. Management of the delayed traumatic medial telecanthaldeformity. Aesthet Surg J. 2010 Jul-Aug;30(4):516-21. doi:10.1177/1090820X10380387. PMID: 20829248.

53: Li D, Zeng W, Tao J, Li S, Liang C, Chen X, Mu W, Wang X, Qin Y, Jie Y, WeiW. Mutations of the transcription factor FOXL2 gene in Chinese patients withblepharophimosis-ptosis-epicanthus inversus syndrome. Genet Test Mol Biomarkers.2009 Apr;13(2):257-68. doi: 10.1089/gtmb.2008.0121. PMID: 19371227.

54: Li D, Jie Y, Liu H, Liu J, Zhu Z, Mao C. Reconstruction of anophthalmicorbits and contracted eye sockets with microvascular radial forearm free flaps.Ophthalmic Plast Reconstr Surg. 2008 Mar-Apr;24(2):94-7. doi:10.1097/IOP.0b013e318166dad1. PMID: 18356711.

55: Liu JM, Chen ZY, Zhu ZH, Li DM. [Eye socket reconstruction with free flap].Zhonghua Zheng Xing Wai Ke Za Zhi. 2006 Sep;22(5):344-6. Chinese. PMID:17144448.

56: Chen T, Min Y, Li DM, Zhao Y, He YL. [Experimental study of using acellulardermal dermis instead of donor sclera in orbital implantation]. Zhonghua ZhengXing Wai Ke Za Zhi. 2005 May;21(3):204-7. Chinese. PMID: 16128106.

著作与译著

《眼部整形美容手术图谱》主编 2008年,人民卫生出版社 《眼睑手术图谱》主编2009年,北京科技出版社 《眼整形外科-手术设计与技术》主译,2003年,人民卫生出版社 《眼科外眼手术》第二版,主编2012年,中华医学会电子音像出版社 《头颈整形外科学》 主译2013年,人民卫生出版社 《眶面部整形手术视频图谱》 主译2014年,人民卫生出版社 《眼整形美容外科图谱》第二版,主编,2016年,人民卫生出版社 《眼睑,结膜与眶部肿瘤图谱》(第三版)主译2018年,人民卫生出版社 《同仁眼整形眼眶病诊疗手册》主编2020年,人民卫生出版社 《眼整形眼眶手术图谱》主译,2020年,人民卫生出版社



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