工作经历
眼科党支部书记,科研副主任。 教育经历: 2001.09 – 2005.07 北京大学,眼科学,博士,导师:王薇 1996.03 – 1998.07 北京医科大学,眼科学,硕士,导师:朱秀安 1991.09 – 1996.03 北京医科大学,临床医学,学士 工作经历: 北医三院院党委委员北医三院教学管理委员会委员 北医三院感染管理委员会委员 北医三院眼科支部书记 北医三院眼科教学秘书 北医三院眼科主任医疗助理
科研工作
(1)北京市自然科学基金,面上项目7202229,“MYH9基因突变导致先天性白内障及其 与F-actin蛋白网络相关性的分子机制研究”,2020.01-2022.12,20万,在研,主持;
(2)国家科技重大专项,2018ZX0101004,东非、中亚和东南亚等区域重要传染病防控 关键保障技术研究-东南亚地区重要传染病防控保障技术研究,2018.01-2020.12,74.3万 ,在研,参加;
(3)北大医学交叉研究种子基金,2021.1-2021.12;眼周经皮穴位电刺激用于延缓儿童近视进展的有效性、安全性研究及其机制探索,在研,主持;
(4)首都卫生发展科研专项,首发2018-2-4093,砭石艾灸红外干眼治疗仪在睑板腺功 能障碍治疗中的有效性及安全性研究,2018.01-2020.12,40万,在研,主持;
(5)首都临床特色应用研究项目,Z141107002514042,角膜共焦激光显微镜在外眼恶性肿瘤诊断及治疗中的应用,2014.01-2016.12,15万,已结题,主持;
学术兼职
中国装备协会视觉康复专委会主委
国际眼表与泪膜协会委员
中国医师协会眼科分会白内障专委会委员
中国民族医学会眼科分会委员
中国医疗保健国际交流促进会药学信息化分会委员
中国医疗保健国际交流促进会眼科分会委员
中国医学教育协会眼科分会常委
中国老年医学会眼科分会常委
卫生部国际交流中心健康跨车教授委员会委员
海峡两岸医学会白内障与视光手术学组委员
北京市医师协会白内障专委会秘书
北京市医师协会常务理事
北京市医学会眼科分会委员
北京市住院医师规范化培训眼科专科委员会委员
Journal of ophthalmology杂志评阅人
中华眼科杂志通讯编委
中华眼科电子版编委
获奖情况
(1)荣获首届“北京大学临床医疗奖”;(2)作为首席科学家和项目主要负责人,主持新型角膜植片“脱细胞真皮基质(ADM)”多中心临床验证,该植片已获得2017年国家科学进步奖提名。
著作与译著
主要论文 (1) Zhang M, Huang C, Wang Z, Lv H, Li X. In silico analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the human GJA3 gene associated with congenital cataract. BMC Mol Cell Biol. 2020;21(1):12. IF=3.485 (2) Hao Y, Xiaodan J, Jiarui Y, Xuemin L. The effect of hormone therapy on the ocular surface and intraocular pressure for postmenopausal women: a systematic review and meta-analysis of randomized controlled trials [published online ahead of print, 2020 Jun]. Menopause. IF=3.305 (3) Wang, Z., Huang, C., Lv, H., Zhang, M., & Li, X. In silico analysis and high-risk pathogenic phenotype predictions of non-synonymous single nucleotide polymorphisms in human Crystallin beta A4 gene associated with congenital cataract. PLoS One. 2020;15(1):e0227859. IF=2.776 (4) Ren X, Wang Y, Wang D, Wu B, Wu L, Xu Y, Yang J, Chen Z, Li X. A novel standardized test system to evaluate dynamic visual acuity post trifocal or monofocal intraocular lens implantation: a multicenter study;EYE. IF=2.336 (5) Wang Y, Ma J, Jiang X, Liu Z, Yang J, Li X.Development of Transparent Acellular Dermal Matrix as Tissue-Engineered Stroma Substitute for Central Lamellar Keratoplasty. Invest Ophthalmol Vis Sci. 2020 Jan 23;61(1):5. doi: 10.1167/iovs.61.1.5. IF=3.812 (6) Wan Y, Wang Y, Zhao L, et al. Correlation among Lens Opacities Classification System III grading, the 25-item National Eye Institute Visual Functioning Questionnaire, and Visual Function Index-14 for age-related cataract assessment. Int Ophthalmol. 2020;40(7):1831-1839. doi:10.1007/s10792-020-01353-0. IF=1.496 (7) Wei S, Ren X, Wang Y, Chou Y, Li X. Therapeutic Effect of Intense Pulsed Light (IPL) Combined with Meibomian Gland Expression (MGX) on Meibomian Gland Dysfunction (MGD). J Ophthalmol. 2020;2020:3684963. Published 2020 Apr 13. doi:10.1155/2020/3684963 IF=1.68 (8) Wang Y, Cui W, Liu R, Tian Y, Ni W, Zhou C. Silicone Oil-Associated Extensive Intraocular Ossification: A case report [published online ahead of print, 2020 Jun 5]. Eur J Ophthalmol. 2020;1120672120925785. doi:10.1177/1120672120925785. IF=1.716 (9) Wang YH, Zhao LM, Liu ZY, Li XM. Perioperative management by WeChat under the haze of COVID-19. Int J Ophthalmol. 2020 Jul 18;13(7):1161-1163. doi: 10.18240/ijo.2020.07.22. PMID: 32685407; PMCID: PMC7321933. (10) Wan Y, Yang J, Ren X, Yu Z, Zhang R, Li X. Evaluation of eye movements and visual performance in patients with cataract. Sci Rep. 2020 Jun 18;10(1):9875. doi: 10.1038/s41598-020-66817-w. PMID: 32555224; PMCID: PMC7303140. (11) Ma J, Wei S, Jiang X, Chou Y, Wang Y, Hao R, Yang J, Li X. Evaluation of objective visual quality in dry eye disease and corneal nerve changes. Int Ophthalmol. 2020 Jul 2. doi: 10.1007/s10792-020-01483-5. Epub ahead of print. PMID: 32617802. (12) Luling Yang, Xuemin Li. Evaluation of Corneal Transparency in Diabetic Patients Aged 60 Years and Over. International Journal of Diabetes and Clinical Research. ESCI (13) Hao R, Chou Y, Wan Y, Jiang X, Li X. Patient satisfaction with the ocular surface individualized medical program. Eur J Ophthalmol. 2020 Jul 28:1120672120945653. doi: 10.1177/1120672120945653. Epub ahead of print. PMID: 32722934. (14) Wan Y, Zhao L, Huang C, Xu Y, Sun M, Yang Y, An L, Lv S, Yu Y, Chen D, Zhou P, Wang Y, Zhang M, Jiang A, Chen Z, Li X. Validation and comparison of the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) and the Visual Function Index-14 (VF-14) in patients with cataracts: a multicentre study. Acta Ophthalmol. 2020 Sep 17. doi: 10.1111/aos.14606. Epub ahead of print. PMID: 32940410. IF=3.362 (15) Tian Y, Wang Y, Liu Z, Li X. Isolated-check visual evoked potential: a more sensitive tool to detect traumatic optic neuropathy after orbital fracture. Graefes Arch Clin Exp Ophthalmol. 2020 Sep 9. doi: 10.1007/s00417-020-04895-2. Epub ahead of print. PMID: 32902756. IF=2.396 (16) Ren X, Chou Y, Jiang X, Hao R, Wang Y, Chen Y, Li X. Effects of Oral Vitamin B1 and Mecobalamin on Dry Eye Disease. J Ophthalmol. 2020 Sep 9;2020:9539674. doi: 10.1155/2020/9539674. PMID: 33005449; PMCID: PMC7508221. IF=1.447 (17) Wang Y, Liu Z, Huang C, Zhao L, Jiang X, Liu Y, Liu Y, Wan Y, Chou Y, Li X. Analysis of lens epithelium telomere length in age-related cataract. Exp Eye Res. 2020 Sep 28;201:108279. doi: 10.1016/j.exer.2020.108279. Epub ahead of print. PMID: 32991882. IF=3.011 (18) Zhenyu Wang, Chen Huang, Xuemin Li. Research trends and hotspots analysis of conjunctival bacteria based on CiteSpace software. Biomed Research International. IF=2.276 (19) Ran Hao, Yan Liu, Xue-min Li, Leptin’s Concentration in Tears and Dry Eye: A Clinical Observational Study. International Journal of Ophthalmology. IF=1.33 (20) Wang Z, Huang C, Sun Y, Lv H, Zhang M, Li X. Novel mutations associated with autosomal-dominant congenital cataract identified in Chinese families. Exp Ther Med. 2019 Oct;18(4):2701-2710. SCI源刊,IF=1.448,Q4 (21) Yang J, Liu Y, Xu Y, et al. A new approach of ocular nebulization with vitamin B12 versus oxytocin for the treatment of dry eye disease: an in vivo confocal microscopy study. Drug Des DevelTher 2019;13:2381-91. SCI源刊,IF=3.208,Q2 (22) Fu J, Chou Y, Hao R, Jiang X, Liu Y, Li X. Evaluation of ocular surface impairment in meibomian gland dysfunction of varying severity using a comprehensive grading scale. Medicine (Baltimore). 2019 Aug;98(31):e16547. SCI源刊,IF=1.87,Q2 (23) Liu Y, Chou Y, Dong X, Liu Z, Jiang X, Hao R, Li X. Corneal Subbasal Nerve Analysis Using In Vivo Confocal Microscopy in Patients With Dry Eye: Analysis and Clinical Correlations. Cornea. 2019 Oct;38(10):1253-1258. SCI源刊,IF=2.313,Q2 (24) Jiang X, Wang Y, Qiu W, Huang C, Liu Z, Ding T, Shi D, Li X. Corneal Stromal Transplantation With Human-derived Acellular Dermal Matrix for Pellucid Marginal Corneal Degeneration: A Nonrandomized Clinical Trial. Transplantation. 2019 Jun;103(6):e172-e179. SCI源刊,IF=4.743,Q1 (25) Yang J, Zhu X, Liu Y, et al. TMIS: a new image-based software application for the measurement of tear meniscus height. Acta Ophthalmol 2019 doi: 10.1111/aos.14107. SCI源刊,IF=3.153,Q1 (26) Tong Ding, Yilin Chou, Xiaodan Jiang, WeiqiangQiu, Danna Shi, Feng Wu, Xuemin Li. a case of blurred vision and viral keratitis postcataract surgery. Future Virol. (2018) 13(12), 829–833. SCI源刊,IF=0.73,Q4 (27) Jiang X, Deng A, Yang J, Bai H, Yang Z, Wu J, Lv H, Li X, Wen T. Pathogens in the Meibomian gland and conjunctival sac: microbiome of normal subjects and patients with Meibomian gland dysfunction. Infect Drug Resist. 2018 Oct 11;11:1729-1740. SCI源刊,IF=3.0,Q2 (28) Lv H, Yang J, Liu Y, Jiang X, Liu Y, Zhang M, Wang Y, Song H, Li X. Changes of intraocular pressure after cataract surgery in myopic and emmetropic patients. Medicine (Baltimore). 2018 Sep;97(38):e12023. SCI源刊,IF=1.87,Q2 (29) Yang Y, Lv H, Wang Y, Jiang X, Zhang M, Li X. Clinical outcomes following trifocal diffractive intraocular lens implantation for age-related cataract in China. Clin Ophthalmol. 2018 Jul 26;12:1317-1324. SCI源刊,IF=0.99,Q1 (30) Song H, Li Y, Zhang Y, Shi D, Li X. Bandage Lenses in the Postoperative Care for Cataract Surgery Patients: A Substitute for Eye Patch? J Ophthalmol. 2018 May 15;2018:1493967. SCI源刊,IF=1.58,Q3 (31) Jiang X, Wang Y, Lv H, Liu Y, Zhang M, Li X.Efficacy of intra-meibomian gland injection of the anti-VEGF agent bevacizumab for the treatment of meibomian gland dysfunction with lid-margin vascularity.Drug Des DevelTher. 2018 May 16;12:1269-1279. SCI源刊,IF=3.208,Q2 (32) Liu Y, Wang Y, Lv H, Jiang X, Zhang M, Li X.α-adrenergic agonist brimonidine control of experimentally induced myopia in guinea pigs: A pilot study. Mol Vis. 2017 Nov 15;23:785-798. SCI源刊,IF=2.174,Q2 (33) Liu Y, Yang J, Tao L, Lv H, Jiang X, Zhang M, Li X. Risk factors of Diabetic Retinopathy in Patients with Type 2 Diabetes Mellitus in Mainland China. BMJ Open. 2017 Sep 1;7(9):e016280. SCI源刊,IF=2.376,Q2 (34) Liu Y, Song Y, Tao L, Qiu W, Lv H, Jiang X, Zhang M, Li X. Prevalence of diabetic retinopathy among 13473 patients with diabetes mellitus in China: a cross-sectional epidemiological survey in six provinces. BMJ Open. 2017 Jan 9;7(1):e013199. SCI源刊,IF=2.376,Q2 (35) Wang Y, Lv H, Liu Y, Jiang X, Zhang M, Li X, Wang W. Characteristicsofsymptomsexperiencedbypersonswithdry eyediseasewhile driving in China. Eye(Lond). 2017 Jun 16. SCI源刊,IF=2.366,Q2 (36) Song H, Zhang M, Hu X, Li K, Jiang X, Liu Y, Lv H, Li X. Correlation Analysis of Ocular Symptoms and Signs in Patients with Dry Eye. J Ophthalmol. 2017;2017:1247138. SCI源刊,IF=1.58,Q3 (37) Mingzhou Zhang, HuibinLv, Chen Huang, Xuemin Li. Targeted exome sequencing identified a novel GJA3 gene missense mutation causing autosomal dominant congenital cataract in a large Chinese family. International Journal of Clinical and Experimental Medicine. SCI源刊,IF=0.181,Q4 (38) Qiu W, Zhang M, Xu T, Liu Z, Lv H, Wang W, Li X. Evaluation of the Effects of Conjunctivochalasis Excision on Tear Stability and Contrast Sensitivity. Sci Rep. 2016 Nov 28;6:37570. SCI源刊,IF=4.011,Q1 (39) Jiang X, Lv H, Song H, Zhang M, Liu Y, Hu X, Li X, Wang W. Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction. J Ophthalmol. 2016;2016:1910694. SCI源刊,IF=1.58,Q3 (40) Yan Liu, HuibinLv, Xiaodan Jiang, Xiaodan Hu, Mingzhou Zhang, Xuemin Li, Intraocular Pressure Changes during Accommodation in Progressing Myopes, Stable Myopes and Emmetropes. PLoS One. 2015,10(10): e0141839. SCI源刊,IF=2.776,Q2 (41) Xiaodan Jiang, HuibinLv, WeiqiangQiu, Ziyuan Liu, Xuemin Li, Wang Wei, Efficiency and safety of subconjunctival injection of anti-VEGF agent - bevacizumab - in treating dry eye. Drug Des DevelTher. 2015 12;9: 3043-50. SCI源刊,IF=3.208,Q2 (42) HuibinLv, Chen Huang, Jing Zhang, Ziyuan Liu, Zhike Zhang, Haining Xu, Yuchen You, Jinping Hu, Xuemin Li, Wei Wang, A novel HSF4 gene mutation causes autosomal-dominant cataracts in a Chinese family. G3 (Bethesda). 2014, 4(5): 823-8. SCI源刊,IF=2.63,Q2 (43) Yan Liu, HuibinLv, Xuemin Li, Accommodation-induced intraocular pressure changes in progressing myopes and emmetropes. Eye (Lond). 2014, 28(11): 1334-40. SCI源刊,IF=2.366,Q2 (44) WeiqiangQiu, Ziyuan Liu, MingxinAo, Xuemin Li, Wei Wang, Punctal plugs versus artificial tears for treating primary Sjo?gren's syndrome with keratoconjunctivitis SICCA: a comparative observation of their effects on visual function. Rheumatol Int. 2013, 33 (10): 2543-8. SCI源刊,IF=2.2,Q3 (45) HuibinLv, Ziyuan Liu, Xuemin Li, Wei Wang. Effect of lacrimal plugs combined with deproteinzed calf blood extract eye gel for filamentary keratitis. J Ocul Biol Dis Infor, 2010, 3(4): 134-40. (46) Sanbao Chai, Xuemin Li, Yongzheng Pang, Yongfen Qi, Chaoshu Tang. Increased plasma levels of endothelin-1 and urotensin-II in patients with coronary heart disease. Heart Vessels. 2010, 25(2): 138-43. SCI源刊,IF=1.62,Q3 (47) MingxinAo, Xuemin Li, Chen Huang, Zhiqiang Hou, WeiqiangQiu, Wei Wang*. Significant improvement in dynamic visual acuity after cataract surgery: a promising potential parameter for functional vision. PLoS One. 2014,9(12):e115812. SCI源刊,IF=2.776,Q2 (48) WeiqiangQiu, Huirong Zhang, Ziyuan Liu, Xuran Dong, Xuemin Li, Wei Wang, Panuveitis complicated by an inflammatory retinal mass. J Ocul Biol Dis Infor. 2013, 5(2): 36-9. (49) Chen Huang, Yongsheng Xu, Xuemin Li, Wei Wang. Vascular endothelial growth factor A polymorphisms and age-related macular degeneration: a systematic review and meta-analysis. Mol Vis. 2013,19:1211-21. SCI源刊,IF=2.174,Q2 (50) WeiqiangQiu, Ziyuan Liu, Zhike Zhang, MingxinAo, Xuemin Li, Wei Wang. Punctal plugs versus artificial tears for treating dry eye: a comparative observation of their effects on contrast sensitivity. J Ocul Biol Dis Infor. 2012 Nov 29;5(1):19-24. (51) Ziyuan Liu, Jing Ji, Jing Zhang, Chen Huang, Zhaojun Meng, WeiqiangQiu, Xuemin Li, Wei Wang. Corneal reinforcement using an acellular dermal matrix for an analysis of biocompatibility, mechanical properties, and transparency. Acta Biomater. 2012,8: 3326-3332. SCI源刊,IF=6.638,Q1 (52) Chen Huang, Jing Zhang, MingxinAo, Ying Li, Chun Zhang, Yonggen Xu, Xuemin Li, Wei Wang. Combination of retinal pigment epithelium cell-conditioned medium and photoreceptor outer segments stimulate mesenchymal stem cell differentiation toward a functional retinal pigment epithelium cell phenotype. J Cell Biochem. 2012,113(2):590-8. SCI源刊,IF=3.448,Q2 (53) MingxinAo, Xiaoyong Chen, Chen Huang, Xuemin Li, Zhiqiang Hou, Xue Chen, Chun Zhang, Wei Wang. Color discrimination by patients with different types of light-filtering intraocular lenses. J Cataract Refract Surg. 2010,36(3):389-95. SCI源刊,IF=2.238,Q2 (54) 王银浩, 刘子源, 李学民. 端粒通过抗氧化应激作用影响年龄相关性白内障的发病过程[J]. 国际眼科纵览, 2020, 44(02):99-104. (55) 于子桐, 杨嘉瑞, 李学民. 干眼对生活质量影响的相关研究进展[J]. 中华眼科医学杂志(电子版), 2020, 010(001):51-57. (56) 洪颖, 丁瞳, 李学民, 王薇, Priyal, S. , & Loewen, N. A. .中美医学生课程设置的对比研究和启示——以北京大学和匹兹堡大学为例. 中华医学教育探索杂志, 2019, 18(4), 342-345.一般期刊 (57) 洪颖, 杨嘉瑞, 李学民, 张纯, 王斯雅, & 王薇.导师团队制在眼科学专业学位研究生培养中的应用研究. 中华医学教育杂志, 2019, 39(3), 219-222.核心期刊 (58) 郝然, 李学民. 干燥综合征分类标准的变化与诊断新进展. 国际眼科杂志 2019,19(10):1713-1716 核心期刊 (59) 李炳震, 李学民. 案例综合教学法在眼科学课程教学中的应用[J]. 中华医学教育探索杂志, 2019, 18(6):588-592.一般期刊 (60) 赵黎明,王震宇,万雨,王银浩,敖明昕,李学民.不同年龄患者选择白内障手术时机变化趋势的临床研究[J].中华眼科医学杂志(电子版),2019,9(03):146-152.一般期刊 (61) 禹晓童,王震宇,黄琛,吕会斌,张明洲,李学民,敖明昕.先天性白内障相关基因热休克转录因子4非同义单核苷酸多态性高危致病表型的预测研究[J].中华眼科医学杂志(电子版),2019,9(02):96-104.一般期刊 (62) 洪颖,杨嘉瑞,李学民,张纯,王斯雅,王薇,导师团队制在眼科学专业学位研究生培养中的应用研究[J].中华医学教育杂志. 2019, 39(3): 219-222核心期刊 (63) 王震宇,黄琛,李学民.重视基因突变位点致病性预测软件在眼科领域的应用.中华眼科医学杂志(电子版),2018(06):241-248.一般期刊 (64) 宋航,张艳,江晓丹,张小艳,李学民.反射式共聚焦显微镜在眼睑肿物诊治中的应用现状.中华眼科医学杂志(电子版),2018,8(03):134-139.一般期刊 (65) 张智科,李学民,王薇.泪小管栓塞治疗白内障术后干眼症的效果评价.中国临床研究,2018,31(06):744-748.一般期刊 (66) 杨洋,张明洲,吕会斌,江晓丹,刘嫣,李学民.周边离焦软性角膜接触镜与单焦点软性角膜接触镜对青少年近视进展控制效果的Meta分析.中华眼科医学杂志(电子版),2017,7(01):25-31.一般期刊 (67) 胡晓丹,江晓丹,吕会斌,刘嫣,张明洲,李学民.瘦素及其与眼科疾病关系的研究进展.中华眼科医学杂志(电子版),2016,6(03):130-135.一般期刊 (68) 胡晓丹,吕会斌,江晓丹,李学民,睑板腺功能障碍与睑板腺脂质改变,中华眼科杂志,2015, 51(3):225-228核心期刊 (69) 刘嫣,刘俊茹,吕会斌,李学民,积极情绪对青年医师白内障超声乳化手术学习的影响,中华医学教育杂志:2014,34(3):459-62.核心期刊 (70) 洪颖,李学民,王薇,以团队为基础学习教学方法在眼科学教学中的应用,中华医学教育杂志:2014,34(1):98-102.核心期刊 (71) 邱伟强,李学民,王薇,刘子源,张志红,泪点栓塞和人工泪液对干眼患者视功能和泪膜稳定性的影响,眼科新进展:2013,33(10):946-8.核心期刊 (72) 敖明昕,王薇,李学民,侯志强,黄琛,超声乳化白内障吸除联合人工晶状体植入术后运动视标分辨力的变化,中华眼科杂志:2013,49(5):405-8 核心期刊 (73) 刘子源,李海平,陈雪,李学民,王薇,Day case手术模式缩短老年性白内障患者住院时间的研究,中国医院:2012,16(4):56-9.一般期刊 (74) 吕会斌,李学民,王薇,实施医学生个性化临床教学管理的实践探索,中华医学教育杂志:2012,32(5):651-6. 核心期刊 (75) 李学民,刘子源,王薇,眼科学客观结构化临床考试合理性和有效性的初步探究,中华医学教育杂志:2011,31(1):150-151.核心期刊 (76) 刘俊茹,李学民,王薇,翼状胬肉术后结膜印记细胞学及临床疗效观察,中华眼科杂志:2010,46(4):323-8.核心期刊 (77) 赵欣,李学民,王欣,王薇,虹膜睫状体囊肿对后房型人工晶状体位置的影响,国际眼科杂志:2008,8(10):2028-31.核心期刊 (78) 赵欣,李学民,王欣,王薇,白内障患者原发性虹膜睫状体囊肿的超声生物显微镜检测,中国实用眼科杂志:2007,25(3):277-9.核心期刊 (79) 李学民,赵欣,胡力中,王薇,白内障患者手术前后干眼的临床观察,中华眼科杂志:2007,43(1):10-13.核心期刊 (80) 李学民,王薇,白细胞介素2在铁粉诱发早期眼内非感染性炎性反应中对晶状体上皮细胞凋亡的影响,中华眼科杂志:2007,43(10):902-905.核心期刊 (81) 李学民,张君,王薇,泪道栓塞术治疗干眼症的临床效果,中华眼科杂志:2005,41(12):1098-120.核心期刊 著作译作: 【眼科学基础】副主编,2007,2 【卫生部“视觉第一,中国行动”眼科医生白内障诊疗培训教材】编者,2003,6 【眼科基本技能】编者,2004,8 【干眼诊疗使用手册】主译 2019,8.