We are equipped with an construction area of 2500 Square Meters, which includes 14 standard Double Wards, corresponding Clinic facilities and 2 Clinic operating theaters, 3 lamina-flow cleanrooms for procedures (oocyte retrieval, and embryo transfer), oocyte culture and ICSI manipulation respectively, and Molecular Biology Laboratory, Endocrine Laboratory etc. with a total of investment reached to 10 million CNY and a total capability of patient receipts as high as 1,500 people per year.

The center has now employed more than 30 staff (10 with Doctorate and 5 with Master’s degree), of which, there are 4 professors and 5 associate professors.

The items currently available for diagnostic and treatment services include infertility from tubal factors, ovulation problems, female endocrine factors, irregular menses, Polycystic Ovary Syndrome (PCOS), male infertility from oligospermia, azoospermia, or immotile spermatozoa, testicular biopsy, ovulation monitoring, test tube baby (IVT-ET), Intracytoplasma sperm injection (ICSI), Preimplantation Genetic Diagnosis (PGD), Artificial Fertilization (IUI &AID), Fallopian Tube Recanalisation—fluid-based, Pathological biopsy on endometrium, checkup or management with hysteroscope or celioscope, female hormone assays, semen routine and chromosome analyses etc.

We have decades of history for treatment on infertility and gynecological endocrine. In 1958, Professor Zhang Lizhu set up the Department of Obstetrics and Gynecology in the third hospital of Beijing Medical college, and during the course of daily work, she found that cases of amenorrhea, irregular menses and infertility by female endocrine dysfunction were very common in patients from North Beijing, as a result, in company with the development of routine Obstetrical and Gynecological services, investigations and management to dysfunctional diseases of female reproductive endocrine are of similar importance as Gynecology, Obstetrics and Family Planning. And today, diagnosis, management and researches regarding infertility and female reproductive endocrine have been featured in the specialty of Obstetrics and Gynecology in our hospital.

Early in the 1960s, most the postgraduates guided by professor Zhang Lizhu had been focusing their researches on Gynecological Endocrine; and then, in 1970, professor Zhang Lizhu set up the first research institute of female reproductive endocrine of our country with jobs developed for hormone determinations, which enable gradually deeper insights upon the female reproductive endocrine and, as a result, a great quantity of patients offered with top level treatment of that time in the nation. After the ten-year turmoil of cultural revolution, and with the resumption of national education system as well as the great attention by the nation to scientific researches, which had greatly promoted the specialty development of female reproductive endocrine and infertility, a great many of high level postgraduates had been educated and they have already become subject leaders and technical pillars in clinics.

In 1986, Professor Zhang Lizhu initiated the first application research on test tube baby technique in China under very harsh conditions. At that time, when oocyte retrieval must resort to abdominal incisions, she chose a strategy that allowed a concurrent oocyte retrieval to occur via ovarian puncture on patients who were undergoing surgeries to remove pelvic lesion that provided a remedy to their resultant infertility, as a result, the procedure greatly ensure the benefits of the patients, namely, the removal of pelvic diseases as well as the treatment on infertility.

In 1989, the first test tube baby of Mainland China was born in the third hospital of Beijing Medical University. And over the last 20 years, apart from the culture of the first test tube in the Mainland, the first test tube baby with oocyte donation, embryo freezing and Gamate Intrafallopian Transfer etc. were also successful, which allowed us a leading position in China and an advanced rank, internationally, in term of clinical diagnoses and management as well as sciences. In this recent decade, Intracytoplasma Sperm Injections (ICSI) have been successfully adopted for male infertility, and Preimplantation Genetic Diagnoses have also been established and applied in the clinical practices. Meanwhile, researches on the development of human pre-antral follicles had resulted in the successful mature and fertilization of immature oocytes, of which, the fruit, only successful in very few countries, were highly praised by Dr. Edwards, the famous scholar and the creator of the World’s fist test tube baby.

Apart from the assisted reproduction, we are also bearing strong technical capability for the diagnoses and management of female endocrine disease in our Center of Reproductive Medicine, especially for Polycystic Ovary Syndrome (PCOS), the diagnoses and management, with over decade’s development, have been in leading position in China and among advanced rank in the world. In addition to standardization to the diagnoses and management, we also perceived that, attention should be paid to the amenorrhea and infertility, as well as to the long term influence upon health from the hyperandrogenemia, insulin-resistance/hyperinsulinemia and fat metabolism disorder and, as a result, administration of dimethyldiguanide (Metformin) to treatment of PCOS was introduced for the first time, which allowed obvious reduction of insulin and androgen level that led to some patients ‘ovulation and menses resumed, and most patients’ dream of pregnancy fulfilled.