工作经历

1990年毕业于北京中医药大学，毕业后一直在北京大学第三医院中医科从事临床、教学和科研工作，历任住院医师、主治医师、副主任医师和主任医师。先后师从著名中医专家、首都国医名师姜良铎教授和中国工程院院士、国医大师王琦教授，分别获得硕士和博士学位。现任北京大学第三医院中医科科主任，科室学术带头人，北京市中西医结合生殖医学研究所副所长，北京大学医学部中西医结合学系副主任，兼任北京中西医结合学会副会长。

科研工作

1.国家自然科学基金面上项目, 82074193, 基于Let-7a miRNA探索补肾调血颗粒改善促排卵大鼠子宫内膜容受性的机制

2.首都卫生发展科研专项，首发2024-2-4098，短期针刺对IVF-ET反复着床失败妊娠结局影响的探索性随机对照研究

3.北京大学第三医院“博采合璧”攻关项目，2404-01-01，培土育种法改善DOR患者卵巢储备功能及IVF-ET妊娠结局的疗效评价及作用机制研究

4.首都卫生发展科研专项, 首发2020-2-40912, 补肾调血中药序贯治疗提高卵巢储备功能减退患者IVF-ET成功率的随机对照研究

5.北京大学第三医院队列建设项目, BYSYDL2022013, 补肾中药对DOR患者卵巢储备功能及IVF-ET结局影响的队列研究

6.北京大学第三医院院临床重点项目, BYSY2018030, 冻融周期中药和针刺短期干预提高妊娠率的随机对照研究

7.首都临床特色应用研究, Z141107002514022, 冻融周期中药针刺改善子宫内膜容受性的临床随机对照研究

8.首都医学科技发展（中医药类）项目, SF-2009-III-33, 中药针灸介入辅助生殖技术提高孕育率的临床随机对照研究

学术兼职

北京中西医结合学会副会长

北京中西医结合学会生殖医学专业委员会主任委员

中华中医药学会综合医院中医药工作委员会副主任委员

北京中医药学会生殖医学分会副主任委员

北京中医药学会临床药学专业委员会副主任委员

中国中药协会女性生殖健康药物研究专业委员会常委

世界中医药学会联合会内科专业委员会常务理事

中华中医药学会生殖医学分会常委

中华中医药学会体质分会常委

北京中医药学会脾胃病分会常委

北京中医药学会妇科专业委员会常委

获奖情况

1.中华中医药学会科学技术奖二等奖（排名第一）

2.全国第四批名老中医学术继承人

3.全国第三批优秀中医临床人才

4.北京市优秀名中医

5.首都中医榜样人物

6.荣耀医者·中华医药贡献奖

7.首都杏林健康卫士·传承育人榜样人物

8.第二届首都群众喜爱的中青年名中医

9.首都中医为民办实事榜样人物暨首都杏林健康卫士

10.海淀区首批名老中医药专家学术经验传承工作优秀指导老师

发表论文

发表SCI及国内核心期刊论文70余篇，列举如下： 

1.Zhang J^#, Hu H^#, Zhu Y^#, Jin Y, Zhang H, Fan R, Ye Y^*, Xin X^*, Li D^*. Bushen Jianpi Tiaoxue Decoction (BJTD) ameliorates oxidative stress and apoptosis induced by uterus ageing through activation of the SIRT1/NRF2 pathway. Phytomedicine. 2025,136:156288.

2. Jin YX, Hu HQ, Zhang JC, Xin XY, Zhu YT, Zhang HL, Fan RW, Ye Y*, Li D*. Research status of polycystic ovary syndrome treatment: a mini review and a bibliometric analysis from 2010 to 2023. Gynecol Endocrinol. 2024,40(1):2405098.

3. Jin YX, Hu HQ, Zhang JC, Xin XY, Zhu YT, Ye Y*, Li D*. Mechanism of mesenchymal stem cells in liver regeneration: Insights and future directions. World J Stem Cells. 2024, 16(9):842-845.

4. Zhang J, Zhu Y, Wang J, Hu H, Jin Y, Mao X, Zhang H, Ye Y*, Xin X*, Li D*. Global burden and epidemiological prediction of polycystic ovary syndrome from 1990 to 2019: a systematic analysis from the Global Burden of Disease Study 2019. Plos One. 2024, 19(7):e0306991.

5. Zhang H#, Ye Y#, Zhao Y, Li S, Jiao P, Yang Y, Jin Y, Zeng L, Zhang H, Chen M, Jiang H, Zhou L, Li J, Li D*, Li R*. Obesity is associated with lower levels of negative emotions in polycystic ovary syndrome in clinical and animal studies. Ann Med. 2024,56(1):2373199.

6. Hu H#, Zhang J#, Xin X, Jin Y, Zhu Y, Zhang H, Fan R, Ye Y*, Li D*. Efficacy of natural products on premature ovarian failure: a systematic review and meta-analysis of preclinical studies. J Ovarian Res. 2024,17(1):46.

7. Zhang JC#, Zhang HL#, Xin XY, Zhu YT, Mao X, Hu HQ, Jin YX, Fan RW, Zhang XH, Ye Y*, Li D*. Mechanisms of Bushen Tiaoxue Granules against controlled ovarian hyperstimulation-induced abnormal morphology of endometrium based on network pharmacology. J Ovarian Res. 2024,17(1):25.

8. Hu HQ, Xin XY, Zhu YT, Fan RW, Zhang HL, Ye Y*, Li D*. Application of mesenchymal stem cell therapy for premature ovarian insufficiency: Recent advances from mechanisms to therapeutics. World J Stem Cells. 2024,16(1):1-6.

9. Hao X, Zu M, Ning J, Zhou X, Gong Y, Han X, Meng Q, Li D*, Ding S*. Antitumor effect of luteolin proven by patient-derived organoids of gastric cancer. Phytother Res. 2023;37(11):5315-5327.

10. Ye Y#, Zhu YT#, Zhang JC, Zhang HL, Fan RW, Jin YX, Hu HQ, Xin XY*, Li D*. Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019. Front Neurol. 2023,14:1216777.

11. Zhang H#, Wang W#, Zhao J, Jiao P, Zeng L, Zhang H, Zhao Y, Shi L, Hu H, Luo L, Fukuzawa I, Li D*, Li R*, Qiao J. Relationship between body composition, insulin resistance, and hormonal profiles in women with polycystic ovary syndrome. Front Endocrinol. 2023;13:1085656.

12. Ye Y#, Xin XY#, Zhang HL, Fan RW, Zhu YT*, Li D*. A modified mouse model of haemorrhagic transformation associated with tPA administration after thromboembolic stroke. Heliyon. 2023,9:e13102.

13. Zhang JC, Zhang HL, Xin XY, Zhu YT, Ye Y*, Li D*. Efficacy of Flavonoids on Animal Models of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Nutrients. 2022,14(19),4128.

14. Ye Y#, Zhu YT#, Xin XY, Zhang JC, Zhang HL*, Li D*. Efficacy of Chinese Herbal Medicine for tPA Thrombolysis in Experimental Stroke: A Systematic Review and Meta-Analysis. Phytomedicine. 2022,100:154072.

15. Ye Y#, Zhang B#, Li Y, Xu HD, Liu XM, Huang SM, Wang R*, Li D*. Yin Huo Tang, a traditional Chinese herbal formula, relives ovariectomy and empty bottle stimulation-induced menopause-like symptoms in mice. Front Endocrinol. 2022,13:994642.

16. Zhang JC, Xin XY, Zhang HL, Zhu YT, Ye Y*, Li D*. The Efficacy of Chinese Herbal Medicine in Animal Models of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2022,2022:4892215.

17. Song W#, Chen J#, Yang G, Liao J, Shen H, Li S, Ding N, Li D*. Research on Herbal Therapies for Osteoarthritis in 2004-2022: A Web of Science-Based Cross-Sectional Bibliometric Analysis. Evid Based Complement Alternat Med. 2022,2022:6522690.

18. Xu Y, Pan CS, Li Q, Zhang HL, Yan L, Anwaier G, Wang XY, Yan LL, Fan JY, Li D*, Han JY*. The Ameliorating Effects of Bushen Huatan Granules and Kunling Wan on Polycystic Ovary Syndrome Induced by Dehydroepiandrosterone in Rats. Front Physiol. 2021,12:525145.

19. Zhang HL, Yi M, Li D*, Li R, Zhao Y*, Qiao J. Transgenerational Inheritance of Reproductive and Metabolic Phenotypes in PCOS Rats. Front Endocrinol. 2020,11:144.

20. Lv BY, Sun HY, Li Q, Zhang HL, Pan CS, Yan L, Fan JY, Li D*, Han JY*. The ameliorating effects of Bushen Tiaoxue Granules and Kunling Wan on impaired angiogenesis and endometrial receptivity in rats following controlled ovarian hyperstimulation. Microcirculation. 2020,27(1):e12581.

21. Zhang H*, Sun J, Xin X, Huo Z, Li D*. Contralateral Electroacupuncture Relieves Chronic Neuropathic Pain in Rats with Spared Nerve Injury. Med Sci Monit. 2018,24:2970-2974.

22. Guo J, Li D*, Liu C, Ji X, Li R, Du X. Effects of Chinese herbs combined with in vitro fertilization and embryo transplantation on infertility: a clinical randomized controlled trial. J Tradit Chin Med. 2014;34(3):267-73.

23. Huo ZJ, Guo J, Li D*. Effects of acupuncture with meridian acupoints and three Anmian acupoints on insomnia and related depression and anxiety state. Chin J Integr Med. 2013,19(3):187-91.