工作经历:2004年获北京大学内科学博士学位,并入职北京大学第三医院神经科工作,2013年转至中心实验室工作。2015-2017斯坦福大学医学院做国家留学基金委公派访问学者。
科研工作:主要从事神经变性病的临床研究,特别是分子遗传学、临床流行病学及疾病相关诱导性多能干细胞的研究。以第一或责任作者发表含Nature Genetics在内的文章30余篇,第一负责人主持国自然基金8项,省部级项目4项。先后获得北医三院先进个人、北医三院优秀工作者、北京大学医学部优秀青年学者、北京市科技新星人才、北医三院优秀科研个人等奖项。先后获得高校科技进步一等奖、中华医学科技进步三等奖、北京市科技进步三等奖各1次。另外, 还长期受邀为Nature Human Behaviour,Nature Communications 和Nucleic Acids Research等10余个杂志审稿,并担任Frontiers in Neuroscience的客座主编。
代表性论文:
1.Ming Gao, Na Liu, Xue Mei Li, Wen Chao Liu, Hong Qi Lin, Yan Wang, Yan S, Chen Huang, Xiaogang Li, MinDeng#. The epidemiology and factors predicting survival of amyotrophic lateral sclerosis in a large Chinese cohort. Chin Med J (Engl),2021 Sep 2. 134(18):2231-2236. doi: 10.1097/CM9.0000000000001679. 【Q1, SCI IF 6.133】
2.Wen Chao Liu*, Na Liu*, Yan Wang, Chen Huang, Yan Fang Li, Hao Wang, Xiao Gang Li, Min Deng#. IPSC-derived motor neurons from ALS patients carrying different SOD1 mutations recapitulate pathological features of ALS. Chin Med J (Engl),2021 Oct. 134(20):2457-2464 10.1097/CM9.0000000000001693 【JQ1, SCI IF 6.133】
3.XiaoDong Ju,WenChao Liu,XiaoGang Li,Na Liu,Nan Zhang,Tao Liu, Min Deng#. Two distinct clinical features and cognitive impairment in amyotrophic lateral sclerosis patients with TARDBP gene mutations in the Chinese population. Neurobiology of Aging, 2016 Feb;38:216.e1-6. doi: 10.1016 【Q1, SCI IF 5.03】
4.Xinxiu Liu, Jiayu Chen, Wenchao liu, Xiaogang Li, Qi Chen, Tao Liu, Shaorong Gao#, MinDeng#.The fused in sarcoma protein forms cytoplasmic aggregates
in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation. Neurogenetics, 2015 Jul;16(3):223-231【SCI IF 2.884】
5.Min Deng*,Ling Wei*, Xianbo Zuo*, Yanghua Tian*, Fei Xie, Panpan Hu, Chunyan Zhu, Fengqiong Yu, Yu Meng, Honghao Wang, Fangfang Zhang, Huijuan Ma, Rong Ye, Huaidong Cheng, Jing Du, Wenwen Dong, Shanshan Zhou, Changqing Wang, Yu Wang, Jingye Wang, Xianwen Chen, Zhongwu Sun, Nong Zhou, Yubao Jiang, Xiuxiu Liu, Xiaogang Li, Nan Zhang, Na Liu, Yingjun Guan, Yongsheng Han, Yongzhu Han, Xinyi Lv, Yu Fu, Hui Yu, Chunhua Xi, Dandan Xie, Qiyuan Zhao, Peng Xie, Xin Wang, Zhijun Zhang, Lu Shen, Yong Cui, Xianyong Yin, Hui Cheng, Bo Liang, Xiaodong Zheng, Tatia M C Lee, Gang Chen, Fusheng Zhou, Jan H Veldink, Wim Robberecht, John E Landers, Peter M Andersen, Ammar Al-Chalabi, Chris Shaw, Chunfeng Liu, Beisha Tang, Shangxi Xiao, Janice Robertson, Fengyu Zhang, Leonard H van den Berg, Liangdan Sun, Jianjun Liu, Sen Yang, Xiaodong Ju, Kai Wang, Xuejun Zhang. Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nature Genetics. 2013; 6(45):697-701【SCI IF 38.33】