工作经历:2014年11月获英国爱丁堡大学博士学位,2019年1月于美国斯坦福大学完成博士后研究。2019年4月入职北京大学第三医院工作至今。现任副研究员,负责细胞平台的细胞代谢等方向工作。
科研工作:围绕“免疫细胞代谢”开展心脑血管疾病、肿瘤免疫微环境研究。主持国家自然科学基金、北京市自然科学基金5项。以第一或通讯作者发表SCI论文16篇。
学术兼职:担任中国族中协会官方杂志Stroke & Vascular Neurology 审稿人、青年编委;Brain X 审稿人、青年编委; 中华脑血管病杂志(电子版)审稿人。
获奖情况:2020年获北京大学第三医院青年学术骨干
代表性论文:
1.Wang Y, Jin H, Wang W, Wang F*, Zhao H*. Myosin1f-mediated neutrophil migration contributes to acute neuroinflammation and brain injury after stroke in mice. Journal of Neuroinflammation, 2019; 16(1):77.;
2.Wang Y, Luo Y, Yao Y, Ji X, Feng L, Du F, Zheng X, Tao T, Zhai X, Li Y, Han P, Xu B, Zhao H*. Silencing the lncRNA Maclpil in pro-inflammatory macrophages attenuates acute experimental ischemic stroke via LCP1 in mice. Journal of Cerebral Blood Flow & Metabolism, 2020 Apr; 40(4):747-759.;
3.Wang Y*, Jin H, Wang Y, Yao Y , Yang C, Meng J, Tan X, Nie Y, Xue L, Xu B, Zhao H, Wang F*. Sult2b1 deficiency exacerbates ischemic stroke by promoting pro-inflammatory macrophage polarization in mice. Theranostics, 2021; 11(20):10074-10090. (First and corresponding author);
4.Wang Y, Xu B, Xue L*. Applications of CyTOF in Brain Immune Component Studies. Engineering, Volume 16, September 2022, Pages 187-197.;
5.Wang Y*, Liu C, Chen Y, Chen T, Han T, Xue L, Xu B. Systemically silencing lncRNA Macipil with siRNA nanoparticles alleviates experimental ischemic stroke by promoting macrophages apoptosis and anti-inflammatory activation. Frontiers in Cardiovascular Medicine. 2022 May 6;9:876087. (First and corresponding author);
6.Wang Y#, Zhang T#, Li C, Guo J, Xu B, Xue L*. Telmisartan attenuates human glioblastoma cells proliferation and oncogenicity by inducing the lipid oxidation. Asia-Pacific Journal of Clinical Oncology. 2021;1-7.
7.Li Y#, Wang Y*#,Yao Y#, Griffiths B, Feng L, Tao T, Wang F, Xu B, Stary C, Zhao H. Systematic study of the immune components after ischemic stroke using CyTOF techniques. Journal of Immunology Research, 2020 Aug 28; 2020:9132410.;
8.Li C#, Wang Y#, Gong Y, Zhang T, Huang J, Tan Z, Xue L. Finding an easy way to harmonize – a review of advances in clinical research and combination strategies of EZH2 inhibitors. Clinical Epigenetics, 2021, Mar 24 13(1):62.;
9.Li C, Song J, Guo Z, Gong Y, Zhang T, Huang J, Cheng R, Yu X, Li Y, Chen L, Ma X, Sun Y, Wang Y*, Xue L*. EZH2 Inhibitors Suppress Colorectal Cancer by Regulating Macrophage Polarization in the Tumor Microenvironment. Frontiers in Immunology 2022 Apr 1;13:8578082022 (co-corresponding author);
10.Tan Z#, Wang Y#, Chen Y, Liu Y, Ma M, Ma Z, Wang C, Zeng H, Xue L*, Yue C*, Wang D. The dynamic feature of macrophage M1/M2 imbalance facilitates the progression of non-traumatic osteonecrosis of the femoral head. Frontiers in Bioengineering and Biotechnology. 2022 Apr 27;10:912133,。
专利项目:
1. 医用消毒垃圾桶(国家实用新型),发明人:王艳,薛丽香,专利号:ZL2021 2 0597117.8
2. 一种用于减缓神经免疫反应治疗脑中风的siRNA纳米颗粒(国家发明专利),发明人:薛丽香,王艳,杨军,王涛,刘维海,杨建岭,专利号:ZL202010408671.7
3. 包含EZH2抑制剂和SCD1抑制剂的抗肿瘤药物组合物及其用途(国家发明专利),发明人:薛丽香,郭正阳,张腾瑞,王艳,孙艳,龚月卿,专利号:ZL202111545151.1
4. 一种用于显微镜的可移动细胞位置定位器(国家实用新型),发明人:王艳,薛丽香,李琛,杨得草,专利号:ZL202123150540.2