近5年发表的国际论文

1) Zhang LJ, Tang L, Huang T, Fan DS. Life course adiposity and amyotrophic lateral sclerosis: a Mendelian randomization study. Ann Neurol 2020; 87(3): 434-41.

2) Xu L#, Chen L#, Wang SF#, Feng JN, Liu LL, Wang JX, Liu GZ, Zhan SY*, Gao P*, Fan DS*. Incidence and prevalence of amyotrophic lateral sclerosis in urban China: a national population-based study. J Neurol Neurosur Ps 2020, 91(5):520-525.;

3) He Jing#, Liu XX#, Tang L, Zhao C, He Ji*, Fan DS*. Whole-exome sequencing identified novel KIF5A mutations in Chinese patients with amyotrophic lateral sclerosis and Charcot-Marie-Tooth Type 2. J Neurol Neurosur Ps 2020; 91(3):326-8.

4) Liu X, Duan X, Zhang Y, Sun A, Fan D. Molecular analysis and clinical diversity of distal hereditary motor neuropathy. Eur J Neurol. 2020 Apr 16. doi: 10.1111/ene.14260.

5) Zhang Y, Fan D, Ji H, Qiao S, Li X. Treatment Adherence and Secondary Prevention of Ischemic Stroke Among Discharged Patients Using Mobile Phone- and WeChat-Based Improvement Services: Cohort Study. JMIR Mhealth Uhealth. 2020 Apr 15;8(4):e16496.

6) Xu L, Liu TX, Liu LL, Yao XY, Chen L, Fan DS, Zhan SY, Wang SF. Global variation in prevalence and incidence of amyotrophic lateral sclesosis: a systematic review and meta-analysis. J Neurol, 2020 Apr;267(4):944-953.

7) Chen L, Tang L, Fan DS. Twelve-month duration as an appropriate criterion for flail arm syndrome. Amyotroph Lat Scl Fr 2020; 21(1-2):29-33.

8) Ye S, Rosenbohm A, B?hm S, Uttner I, Ji Y, Ludolph AC, Lulé D, Fan DS. Cognitive and behavioural impairments in German and Chinese ALS populations – a post-hoc comparison of national study data. Amyotroph Lat Scl Fr 2019;20(1-2):28-36.

9) Dorst J, Chen L, Rosenbohm A, Schuster J, Hübers A, Dreyhaupt J, Gess B, Meyer T, Weyen U, Hermann A, Winkler J, Grehl T, Hagenacker T, Lingor P, Koch JC, Emmer A, Petri S, Gro?kreutz J, Metelmann M, Wolf J, Winkler A, Klopstock T, Boentert M, Johannesen S, Storch A, Schrank B, Zeller D, Liu XL, Tang L, Fan DS , Ludolph AC. Prognostic factors in ALS: a comparison between Germany and China. J Neurol 2019; 266:1516-25.

10) Tang L, Ma Y, Liu XL, Chen L, Fan DS. Better survival in female SOD1-mutant patients with ALS: a study of SOD1-related natural history. Translational Neurodegeneration 2019; 8:2

11) Liu XY, Wu CJ, He J, Zhang N, Fan DS. Two rare variants of the ANXA11 gene identified in Chinese ALS patients. Neurobiol Aging 2019; 74:235e9-12.

12) Yu F, Liu XL, Yang Q, Fu Y, Fan DS. In-hospital recurrence in a Chinese large cohort with acute ischemic stroke. Sci Rep 2019; 9:14945.

13) Chen Y, Xia KL, Chen L, Fan DS. Increased Interleukin-6 levels in the astrocyte-derived exosomes of sporadic ALS patients. Frontiers in Neuroscience 2019; 13:574.

14) Zhang Q, Vallerga CL, Walker RM, Lin T, Henders AK, Montgomery GW, He J, Fan DS, Fowdar J, Kennedy M, Pitcher T, Pearson J, Halliday G, Kwok JB, Hickie I, Lewis S, Anderson T, Silburn PA, Mellick GD, Harris SE, Redmond P, Murray AD, Porteous DJ, Haley CS, Evans KL, Mcintosh AM, Yang J, Gratten J, Marioni RE, Wray NR, Deary IJ, McRae AF, Visscher PM. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Med 2019;11:54.

15) Zhang LJ, Chen L, Fan DS. The protective role of pre-morbid type 2 diabetes in patients with amyotrophic lateral sclesosis: a centre-based survey in China. Amyotroph Lat Scl Fr 2019 Dec 18:1-7.

16) Liu XY, Zhang YS, Sun AP, Chen L, Huang X, Zhong YF, Zheng DF, Fan DS. A novel MYH7 mutation resulting in Laing distal myopathy in a Chinese family. Chinese Med J-Peking 2019; 132:856-9.

17) Wu C, Sun Q, Fan D. Serial Magnetic Resonance Imaging Changes in a Patient With Late-Onset Cobalamin C Disease With a Misdiagnosis of Metachromatic Leukodystrophy. JAMA Neurol. 2018 Mar 1;75(3):374-375.

18) Li J, He J, Tang L, Chen L, Ma Y, Fan DS. Screening for TUBA4A mutations in a large Chinese cohort of patients with ALS: re-evaluating the pathogenesis of TUBA4A in ALS. J Neurol Neurosur Ps 2018; 89(12):1350-1352.

19) Tian DY, Li J, Tang L, Zhang N, Fan DS. Screening for CCNF mutations in a Chinese amyotrophic lateral sclerosis cohort. Front Aging Neurosci; 2018;10:185.

20) Xu LP, Li J, Tian DY, He J, Chen L, Tang L, Fan DS. The rs696880 polymorphism in Nogo-A receptor gene (RTN4R) is associated with susceptibility to sporadic amyotrophic lateral sclerosis in Chinese. Front Aging Neurosci 2018;10:108.

21) Liu XL, He J, Gao FB, Gitler AD, Fan DS . The epidemiology and genetics of amyotrophic lateral sclerosis in China. Brain Res 2018;1693(Pt.A):121-6.

22) Tang L, Ma Y, Liu XL, Chen L, Fan DS. Identification of an A4V SOD1 mutation in a Chinese patient with amyotrophic lateral sclerosis without the A4V founder effect common in North America. Amyotroph Lat Scl Fr 2018;19(5-6):466-8.

23) Li J, Ruskey JA, Arnulf I, Dauvilliers Y, Hu MTM, H?gl B, Leblond CS, Zhou S, Ambalavanan A, Ross JP, Bourassa CV, Spiegelman D, Laurent SB, Stefani A, Charley Monaca C, Cochen De Cock V, Boivin M, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Labbe C, Ferman TJ, Dion PA, Fan D, Desautels A, Gagnon JF, Dupré N, Fon EA, Montplaisir JY, Boeve BF, Postuma RB, Roule au GA, Ross OA, Gan-Or Z. Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder. Mov Disord. 2018 Jul;33(6):1016-1020.

24) Tian D, Yang Q, Dong Q, Li N, Yan B, Fan D. Trends in stroke subtypes and vascular risk factors in a stroke center in China over 10 years. Sci Rep. 2018 Mar 22;8(1):5037.

25) Tian DY, Fan DS. Risk Factors, Regional Disparity and Trends of Ischemic Stroke Etiologic Subtypes. Chin Med J (Engl). 2018 Jan 20;131(2):127-129.

26) Benyamin B, He J, Zhao QY, Gratten J, Garton F, Leo PJ, Liu ZJ, Mangelsdorf M, Al-Chalabi A, Anderson L, Butler TJ, Chen L, Chen XD, Cremin K, Deng HW, Devine M, Edson J, Fifita JA, Furlong S, Han YY, Harris J, Henders AK, Jeffree RL, Jin ZB, Li ZS, Li T, Li MM, Lin Y, Liu XL, Marshall M, McCann EP, Mowry BJ, Ngo S, Pamphlett R, Ran S, Reutens DC, Rowe DB, Sachdev P, Shah S, Song S, Tan LJ, Tang L, van den Berg LH, van Rheenen W, Veldink JH, Wallace RH, Wheeler L, Williams KL, Wu JY, Wu X, Yang J, Yue WH, Zhang ZH, Zhang D, Noakes PG, Blair IP, Henderson RD, McCombe PA, Visscher PM, Xu HJ, Bartlett PF, Brown MA*, Wray NR*, Fan DS*. Cross-ethnic meta-analyses identifies association of the GPX3-TNIP1 locus with amyotrophic lateral sclerosis. Nat Commun 2017;8:611

27) Shen S, He J, Tang L, Zhang N, Fan DS. CHCHD10 mutations in patients with amyotrophic lateral sclerosis in mainland China. Neurobiol Aging 2017;54:214.e7-10.

28) Gratten J, Zhao QY, Benyamin B, Garton F, He J, Leo PJ, Mangelsdorf M, Anderson L, Zhang ZH, Chen L, Chen XD, Cremin K, Deng HW, Edson J, Han YY, Harris J, Henders AK, Jin ZB, Li ZS, Lin Y, Liu XL, Marshall M, Mowry BJ, Ran S, Reutens DC, Song S, Tan LJ, Tang L, Wallace RH, Wheeler L, Wu JY, Yang J, Xu HJ, Visscher PM, Bartlett PF, Brown MA*, Wray NR*, Fan DS*. Whole-exome sequencing in amyotrophic lateral sclerosis suggests NEK1 is a risk gene in Chinese. Genome Med 2017;9:97

29) Xu LP, Tian DY, Li J, Chen L, Tang L, Fan DS. The analysis of two BDNF polymorphisms G196A/C270T in Chinese sporadic amyotrophic lateral sclerosis. Front Aging Neurosci 2017;9:135.

30) Liu XY, Yang LP, Tang L, Chen L, Liu XL, Fan DS. DCTN1 gene analysis in Chinese patients with sporadic amyotrophic lateral sclerosis. PLoS One 2017;12(8):e0182572.

31) Zhang HG, Chen L, Tang L, Zhang N, Fan DS. Clinical features of isolated bulbar palsy of amyotrophic lateral sclerosis in China. Chinese Med J-Peking 2017;130:1768-72.

32) Yang Q, Churilov L, Fan D, Davis S, Yan B. 1.4 times increase in atrial fibrillation-related ischemic stroke and TIA over 12years in a stroke center. J Neurol Sci. 2017 Aug 15;379:1-6.

33) Huang X, Fan D. A novel mutation of BICD2 gene associated with juvenile amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener. 2017 Aug;18(5-6):454-456

34) Ye S, Ji Y, Li CY, He J, Liu XL, Fan DS. The Edinburgh cognitive and behavioural ALS screen in a Chinese amyotrophic lateral sclerosis population. PLoS One 2016;11(5):e0155496.

35) Xu LP, Li J, Tang L, Zhang N, Fan DS. MATR3 mutation analysis in a Chinese cohort with sporadic amyotrophic lateral sclerosis. Neurobiol Aging 2016;38:218.e3-4.

36) Chen L, Liu XL, Tang L, Zhang N, Fan DS. Long-term use of riluzole could improve the prognosis of sporadic amyotrophic lateral sclerosis patients: a real-world cohort study in China. Front Aging Neurosci 2016;8:246.

37) Li J, He J, Tang L, Chen L, Xu LP, Ma Y, Zhang N, Fan DS. TUBA4A may not be a significant genetic factor in Chinese amyotrophic lateral sclerosis patients. Amyotroph Lat Scl Fr 2016;17(1):148-50.

38) Wu C, Fan D. A Novel Missense Mutation of the DDHD1 Gene Associated with Juvenile Amyotrophic Lateral Sclerosis. Front Aging Neurosci. 2016 Dec 6;8:291.

39) Chen L, Zhang B, Chen R, Tang L, Liu R, Yang Yan, Yang Yi, Liu XL, Ye S, Zhan SY, Fan DS. Natural history and clinical features of sporadic amyotrophic lateral sclerosis in China. J Neurol Neurosur Ps 2015;86(10):1075-81.

40) He J, Mangelsdorf M, Fan DS, Bartlett P, Brown MA. Amyotrophic lateral sclerosis genetic studies from genome-wide association mapping to genome sequencing. Neuroscientist 2015;21:599-615.

41) He J, Tang L, Benyamin B, Shah S, Hemani G, Liu R, Ye S, Liu XL, Ma Y, Zhang HG, Cremin K, Leo P, Wray NR, Visscher PM, Xu HJ, Brown MA, Bartlett PF, Mangelsdorf M, Fan DS. C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis. Neurobiol Aging 2015;36(7):2660.e1-8.

42) Li CY, Ji Y, Tang L, Zhang N, He J, Ye S, Liu XL, Fan DS. Optineurin mutations in patients with sporadic amyotrophic lateral sclerosis in China. Amyotroph Lat Scl Fr 2015;16(7-8):485-9.

43) Yang Y, Tang L, Zhang N, Pen L, Hadano S, Fan DS. Six SQSTM1 mutations in a Chinese amyotrophic lateral sclerosis cohort. Amyotroph Lat Scl Fr 2015;16(5-6):378-84.

44) Yang Q, Zhang B, Deng P, Chen L, Wang JR, Fan DS. Assessing cardiovascular health using Life’s Simple 7 in a Chinese population undergoing stroke prevention. Chinese Med J-Peking 2015;128:2450-6.