工作经历:
2015年8月入职北京大学大学第三医院检验科,历任助理研究员、副研究员
科研工作:
2022年获批北京市科技新星
主持包括2项国家自然科学基金、1项北京市自然科学基金在内的国家级、省部级、校级及横向基金项目共计10项
参与多项国家自然科学基金重大研究计划重点项目
学术兼职:
中西医结合学会检验医学分会“肿瘤分子诊断专家委员会”委员
北京医学会第十三届检验医学分会学组委员
Traditional Medicine Research 青年编委
《临床与病理杂志》青年编委
发表论文:
以第一作者或通讯作者(含共同)发表学术论文12篇,其中3篇影响因子大于30分。
1.Liu X#, Si W#, He L, Yang J, Peng Y, Ren J, Liu X, Jin T, Yu H, Zhang Z, Cheng X, Zhang W, Xia L, Huang Y, Wang Y, Liu S, Shan L, Zhang Y, Yang X, Li H, Liang J, Sun L*, Shang Y*. The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry. Signal Transduct Target Ther, 2021, 6(1):375.
2.Si W, Huang W, Zheng Y, Yang Y, Liu X, Shan L, Zhou X, Wang Y, Su D, Gao J, Yan R, Han X, Li W, He L, Shi L, Xuan C, Liang J, Sun L, Wang Y*, Shang Y*. Dysfunction of the reciprocal feedback loop between GATA3- and ZEB2-nucleated repression programs contributes to breast cancer metastasis. Cancer Cell. 2015, 27(6):822-836.
3.Liu X#, Si W#, Liu X, He L, Ren J, Yang Z, Yang J, Li W, Liu S, Pei F, Yang X, Sun L*. JMJD6 promotes melanoma carcinogenesis through regulation of the alternative splicing of PAK1, a key MAPK signaling component. Mol cancer. 2017, 16(1):175.
4.Si W*, Zhou J, Zhao Y, Zheng J, Cui L*. SET7/9 promotes multiple malignant processes in breast cancer development via RUNX2 activation and is negatively regulated by TRIM21. Cell Death Dis. 2020, 11(2):151.
5.Liu X, Qiao Y, Ting X, Si W*. Isocitrate dehydrogenase 3A, a rate-limiting enzyme of the TCA cycle, promotes hepatocellular carcinoma migration and invasion through regulation of MTA1, a core component of the NuRD complex. Am J Cancer Res, 2020, 10(10):3212-3229.
6.Si W#, Liu X#, Wei R, Zhang Y, Zhao Y, Cui L*, Hong T*. MTA2-mediated inhibition of PTEN leads to pancreatic ductal adenocarcinoma carcinogenicity. Cell Death Dis. 2019, 10(3):206.
7.Si W#*, Zhao Y#, Zhou J, Zhang Q, Zhang Y. The coordination between ZNF217 and LSD1 contributes to hepatocellular carcinoma progress and is negatively regulated by miR-101. Exp Cell Res. 2019, 379(1):1-10.
8.张蔷,刘旭骏,张园,安美憧,司文喆*. 转移相关蛋白1在胰腺癌中高表达的临床意义及其作用机制分析. 中国临床药理学杂志. 2019, 35(17):1854-1857.
9.叶尔那尔·哈再斯汗#,刘旭骏#,司文喆*. 血清 DNMT1 与 TET1 表达量在肺癌诊断中的临床价值研究. 临床与病理杂志. 2023, 43(1): 1-8.
10.张静,刘旭骏,司文喆*. 男性门诊患者解脲脲原体、淋病奈瑟菌和沙眼衣原体感染的调查分析. 中国临床药理学杂志. 2023,39(1):17-21.